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Laboratoire de chémo-biologie synthétique & thérapeutique | CBST | UMR 7199 de chémo-biologie synthétique & thérapeutique | CBST UMR 7199 de l'Université de Strasbourg et du CNRS
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Laboratoire de chémo-biologie synthétique & thérapeutique | CBST | UMR 7199 de chémo-biologie synthétique & thérapeutique | CBST UMR 7199 de l'Université de Strasbourg et du CNRS
  • LinkedIn
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  • Laboratory of Synthetic and Therapeutic Chemo-Biology | CBST | UMR 7199 Home
  • Laboratory
    • Governance
    • Organizational chart
    • Internal regulations
    • Platforms
    • Collective responsibilities
    • Techniques and equipement
    • Measuring devices
  • Teams
    • Ion Channel Engineering
    • BioFunctional Chemistry
    • Smart NanoParticles
    • Chemistry of Photoresponsive Systems
  • Publications
  • Public
    • The unexpected escapes of the CNRS
    • Ose la recherche, 2025 edition
    • Radiophonic postcast on RCF | ITN TACT
    • Publication of a graphic novel
    • Interview of Guilhem Chaubet on the national Swiss radio RTS | ITN TACT project
    • European project ITN TACT
    • Les molécules du toucher
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Laboratoire de chémo-biologie synthétique & thérapeutique | CBST UMR 7199
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  1. Laboratory of Synthetic and Therapeutic Chemo-Biology | CBST | UMR 7199
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  3. BioFunctional Chemistry
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Publications

Teams

  • Ion Channel Engineering
  • BioFunctional Chemistry
    • News
    • Events
    • Members
    • Publications
  • Smart NanoParticles
  • Chemistry of Photoresponsive Systems

Contacts

88 publications disponibles

  • Articles scientifiques
  • Conférences

Articles scientifiques

  • Antibody-Vincristine Conjugates as Potent Anticancer Therapeutic Agents, Journal of Medicinal Chemistry | 2024
    Co-auteur·e·s : Agathe Boos - Julien Most - Heloise Cahuzac - Louis Moreira Da Silva - François Daubeuf - Stéphane Erb - Sarah Cianferani - Oscar Hernandez Alba - Constantin Semenchenko - Igor Dovgan - Sergii Kolodych - Alexandre Detappe - Françoise Dantzer - Alain Wagner - Maria Zeniou - Guilhem Chaubet
  • Chemical Production of Cytotoxic Bispecific Antibodies Using the Ugi Multicomponent Reaction, ChemBioChem | 2024
    Co-auteur·e·s : Valentine Vaur - Ilias Koutsopetras - Stéphane Erb - Bianka Jackowska - Rania Benazza - Heloise Cahuzac - Alexandre Detappe - Oscar Hernandez Alba - Sarah Cianferani - Christopher J. Scott - Guilhem Chaubet
  • Drug upgrade: A complete methodology from old drug to new chemical entities using Nematic Protein Organization Technique, Drug Development Research | 2024
    Co-auteur·e·s : Judith Eschbach - Alain Wagner - Corinne Beahr - Akkiz Bekel - Anne-Sophie Korganow - Angélique Quartier - Jean-christophe Peter - Pierre Eftekhari
  • Protocol to generate, purify, and analyze antibody-oligonucleotide conjugates from off-the-shelf antibodies, STAR Protocols | 2024
    Co-auteur·e·s : Tony Rady - Victor Lehot - Julien Most - Stéphane Erb - Sarah Cianferani - Guilhem Chaubet - Nicolas Basse - Alain Wagner
  • Retinoids Molecular Probes by Late‐stage Azide Insertion – Functional Tools to Decrypt Retinoid Metabolism, ChemBioChem | 2024
    Co-auteur·e·s : Jessica Coulleray - Alexia Kindler - Mohamad Rima - Heloise Cahuzac - Natacha Rochel - Guilhem Chaubet - Wojciech Krężel - Alain Wagner
  • SEC-MS in denaturing conditions (dSEC-MS) for in-depth analysis of rebridged monoclonal antibody-based formats, Talanta | 2024
    Co-auteur·e·s : Rania Benazza - Ilias Koutsopetras - Valentine Vaur - Guilhem Chaubet - Oscar Hernandez Alba - Sarah Cianferani
  • Site‐Selective Protein Conjugation by a Multicomponent Ugi Reaction, Chemistry - A European Journal | 2024
    Co-auteur·e·s : Ilias Koutsopetras - Valentine Vaur - Rania Benazza - Helene Diemer - Charlotte Sornay - Yağmur Ersoy - Léa Rochet - Carmen Longo - Oscar Hernandez Alba - Stéphane Erb - Alexandre Detappe - Arne Skerra - Alain Wagner - Sarah Cianferani - Guilhem Chaubet
  • Supramolecular Bioconjugation Strategy for Antibody-Targeted Delivery of siRNA, Bioconjugate Chemistry | 2024
    Co-auteur·e·s : Manon Ripoll - Heloise Cahuzac - Igor Dovgan - Sylvain Ursuegui - Patrick Neuberg - Stéphane Erb - Sarah Cianferani - Antoine Kichler - Jean-Serge Remy - Alain Wagner
  • Targeted delivery of immune-stimulating bispecific RNA, inducing apoptosis and anti-tumor immunity in cancer cells, iScience | 2024
    Co-auteur·e·s : Tony Rady - Stéphane Erb - Safia Deddouche-Grass - Renaud Morales - Guilhem Chaubet - Sarah Cianferani - Nicolas Basse - Alain Wagner
  • Cysteine‐Cysteine Cross‐Conjugation of both Peptides and Proteins with a Bifunctional Hypervalent Iodine‐Electrophilic Reagent, Chemistry - A European Journal | 2023
    Co-auteur·e·s : Ilias Koutsopetras - Abhaya Kumar Mishra - Rania Benazza - Oscar Hernandez Alba - Sarah Cianferani - Guilhem Chaubet - Stefano Nicolai - Jérôme Waser
  • Microfluidic Droplet Stabilization via SPAAC Promoted Antibody Conjugation at the Water/Oil Interface, ACS Applied Materials and Interfaces | 2023
    Co-auteur·e·s : Robin Dufossez - Marie-Pierre Krafft - Sylvain Ursuegui - Michel Mosser - Safae Mouftakhir - Ketty Pernod - Guilhem Chaubet - Michaël Ryckelynck - Alain Wagner
  • Reinvestigation of the Automated Synthesis of Stoichiometrically Conjugated Antibodies to Access High Molecular Weight Payloads and Multiplexed Conjugation via an In-Solution Trans-Tagging Process, ACS Omega | 2023
    Co-auteur·e·s : Victor Lehot - Ondřej Lidický - Julien Most - Stéphane Erb - Igor Dovgan - Artem Osypenko - Oleksandr Koniev - Sergii Kolodych - Lenka Kotrchová - Guilhem Chaubet - Sarah Cianferani - Tomáš Etrych - Alain Wagner
  • Targeted Anticancer Agent with Original Mode of Action Prepared by Supramolecular Assembly of Antibody Oligonucleotide Conjugates and Cationic Nanoparticles, Pharmaceutics | 2023
    Co-auteur·e·s : Victor Lehot - Patrick Neuberg - Manon Ripoll - François Daubeuf - Stéphane Erb - Igor Dovgan - Sylvain Ursuegui - Sarah Cianferani - Antoine Kichler - Guilhem Chaubet - Alain Wagner
  • A Novel Family of Acid-Cleavable Linker Based on Cyclic Acetal Motifs for the Production of Antibody-Drug Conjugates with High Potency and Selectivity, Bioconjugate Chemistry | 2022
    Co-auteur·e·s : Tony Rady - Lorenzo Turelli - Marc Nothisen - Elisabetta Tobaldi - Stéphane Erb - Fabien Thoreau - Oscar Hernandez Alba - Sarah Cianferani - François Daubeuf - Alain Wagner - Guilhem Chaubet
  • An overview of chemo- and site-selectivity aspects in the chemical conjugation of proteins, Royal Society Open Science | 2022
    Co-auteur·e·s : Charlotte Sornay - Valentine Vaur - Alain Wagner - Guilhem Chaubet
  • Bicyclo[6.1.0]nonyne carboxylic acid for the production of stable molecular probes, RSC Advances | 2021
    Co-auteur·e·s : Tony Rady - Michel Mosser - Marc Nothisen - Stéphane Erb - Igor Dovgan - Sarah Cianferani - Alain Wagner - Guilhem Chaubet
  • Non-specific interactions of antibody-oligonucleotide conjugates with living cells, Scientific Reports | 2021
    Co-auteur·e·s : Victor Lehot - Isabelle Kuhn - Marc Nothisen - Stéphane Erb - Sergii Kolodych - Sarah Cianferani - Guilhem Chaubet - Alain Wagner
  • Automated linkage of proteins and payloads producing monodisperse conjugates, Chemical Science | 2020
    Co-auteur·e·s : Igor Dovgan - Alexandre Hentz - Oleksandr Koniev - Anthony Ehkirch - Steve Hessmann - Sylvain Ursuegui - Sébastien Delacroix - Margaux Riomet - Frédéric Taran - Sarah Cianferani - Sergii Kolodych - Alain Wagner
  • Ethynylation of Cysteine Residues: From Peptides to Proteins in Vitro and in Living Cells, Angewandte Chemie International Edition | 2020
    Co-auteur·e·s : Romain Tessier - Raj Kumar Nandi - Brendan G. Dwyer - Daniel Abegg - Charlotte Sornay - Javier Ceballos - Stéphane Erb - Sarah Cianferani - Alain Wagner - Guilhem Chaubet - Alexander Adibekian - Jerome Waser
  • Investigating Ugi/Passerini Multicomponent Reactions for the Site‐Selective Conjugation of Native Trastuzumab, Chemistry - A European Journal | 2020
    Co-auteur·e·s : Charlotte Sornay - Steve Hessmann - Stephane Erb - Igor Dovgan - Anthony Ehkirch - Thomas Botzanowski - Sarah Cianferani - Alain Wagner - Guilhem Chaubet
  • Manniindole, an indole derivative from the roots of Anonidium mannii and combined antischistosomal and enzymatic activities, Natural Product Research | 2020
    Co-auteur·e·s : Josette Linda Toussi Matchi - Diderot Tchamo Noungoue - Isabelle Kuhn - Jérôme Boissier - Jean Claude Tchouankeu - Marc Nothisen - Guilhem Chaubet - Delphine Garnier - Sylvain Ursuegui - Silvère Augustin Ngouela - Alain Wagner
  • On the use of DNA as a linker in antibody-drug conjugates: synthesis, stability and in vitro potency, Scientific Reports | 2020
    Co-auteur·e·s : Igor Dovgan - Anthony Ehkirch - Victor Lehot - Isabelle Kuhn - Oleksandr Koniev - Sergii Kolodych - Alexandre Hentz - Manon Ripoll - Sylvain Ursuegui - Marc Nothisen - Sarah Cianferani - Alain Wagner
  • Antibody–Oligonucleotide Conjugates as Therapeutic, Imaging, and Detection Agents, Bioconjugate Chemistry | 2019
    Co-auteur·e·s : Igor Dovgan - Oleksandr Koniev - Sergii Kolodych - Alain Wagner
  • Design and evaluation of ionizable peptide amphiphiles for siRNA delivery, International Journal of Pharmaceutics | 2019
    Co-auteur·e·s : Patrick Neuberg - Alain Wagner - Jean-Serge Remy - Antoine Kichler
  • Sydnone-based turn-on fluorogenic probes for no-wash protein labeling and in-cell imaging, Chemical Communications | 2019
    Co-auteur·e·s : Lucie Plougastel - Manas R. Pattanayak - Margaux Riomet - Sarah Bregant - Antoine Sallustrau - Marc Nothisen - Alain Wagner - Davide Audisio - Frédéric Taran
  • Arginine-selective bioconjugation with 4-azidophenyl glyoxal: application to the single and dual functionalisation of native antibodies, Organic and Biomolecular Chemistry | 2018
    Co-auteur·e·s : Igor Dovgan - Stéphane Erb - Steve Hessmann - Sylvain Ursuegui - Chloé Michel - Christian Muller - Guilhem Chaubet - Sarah Cianferani - Alain Wagner
  • Co-delivery of anti-PLK-1 siRNA and camptothecin by nanometric polydiacetylenic micelles results in a synergistic cell killing, RSC Advances | 2018
    Co-auteur·e·s : Manon Ripoll - Marie Pierdant - Patrick Neuberg - Dominique Bagnard - Alain Wagner - Antoine Kichler - Jean-Serge Remy
  • Expedient synthesis of trifunctional oligoethyleneglycol-amine linkers and their use in the preparation of PEG-based branched platforms, Organic and Biomolecular Chemistry | 2018
    Co-auteur·e·s : Sylvain Ursuegui - Jérémy Schneider - Claire Imbs - Florian Lauvoisard - Marta Dudek - Michel Mosser - Alain Wagner
  • Inhibition of dengue virus infection by mannoside glycolipid conjugates, Antiviral Research | 2018
    Co-auteur·e·s : Evelyne Schaeffer - Vincent Flacher - Patrick Neuberg - Astrid Hoste - Adrien Brulefert - Jean-daniel Fauny - Alain Wagner - Christopher G Mueller
  • Polydiacetylenic nanofibers as new siRNA vehicles for in vitro and in vivo delivery, Nanoscale | 2018
    Co-auteur·e·s : Patrick Neuberg - Imene Hamaidi - Sabrina Danilin - Manon Ripoll - Veronique Lindner - Marc Nothisen - Alain Wagner - Antoine Kichler - Thierry Massfelder - Jean-Serge Remy
  • Recent, non-classical, approaches to antibody lysine modification, Drug Discovery Today: Technologies | 2018
    Co-auteur·e·s : Guilhem Chaubet - Fabien Thoreau - Alain Wagner
  • Reduction–rebridging strategy for the preparation of ADPN-based antibody–drug conjugates, MedChemComm | 2018
    Co-auteur·e·s : Oleksandr Koniev - Igor Dovgan - Brigitte Renoux - Anthony Ehkirch - Jitka Eberova - Sarah Cianferani - Sergii Kolodych - Sébastien Papot - Alain Wagner
  • Synthesis and Kinetic evaluation of an azido analogue of methylerythritol phosphate: a Novel Inhibitor of E. coli YgbP/IspD, Scientific Reports | 2018
    Co-auteur·e·s : Zoljargal Baatarkhuu - Philippe Chaignon - Franck Borel - Jean-Luc Ferrer - Alain Wagner - Myriam Seemann
  • Acyl Fluorides: Fast, Efficient, and Versatile Lysine-Based Protein Conjugation via Plug-and-Play Strategy, Bioconjugate Chemistry | 2017
    Co-auteur·e·s : Igor Dovgan - Sylvain Ursuegui - Stéphane Erb - Chloé Michel - Sergii Kolodych - Sarah Cianferani - Alain Wagner
  • An in vivo strategy to counteract post-administration anticoagulant activity of azido-Warfarin, Nature Communications | 2017
    Co-auteur·e·s : Sylvain Ursuegui - Marion Recher - Wojciech Krężel - Alain Wagner
  • Bioorthogonal Click and Release Reaction of Iminosydnones with Cycloalkynes, Angewandte Chemie International Edition | 2017
    Co-auteur·e·s : Sabrina Bernard - Davide Audisio - Margaux Riomet - Sarah Bregant - Antoine Sallustrau - Lucie Plougastel - Elodie Decuypere - Sandra Gabillet - Ramar Arun Kumar - Jijy Elyian - Thi Minh Nguyet Trinh - Oleksandr Koniev - Alain Wagner - Sergii Kolodych - Frédéric Taran
  • Development and evaluation of beta-galactosidase-sensitive antibody-drug conjugates, European Journal of Medicinal Chemistry | 2017
    Co-auteur·e·s : Sergii Kolodych - Chloé Miche - Sébastien Delacroix - Oleksandr Koniev - Anthony Ehkirch - Jitka Eberova - Sarah Cianferani - Brigitte Renoux - Wojciech Krężel - Pauline Poinot - Christian Muller - Sébastien Papot - Alain Wagner
  • Identification of autoreactive B cells with labeled nucleosomes, Scientific Reports | 2017
    Co-auteur·e·s : Vincent Gies - Alain Wagner - Cécile Seifert - Aurélien Guffroy - Jean-Daniel Fauny - Anne-Marie Knapp - Jean-Louis Pasquali - Thierry Martin - Hélène Dumortier - Anne-Sophie Korganow - Pauline Soulas-Sprauel
  • Structural investigation of cyclo-dioxo maleimide cross-linkers for acid and serum stability, Organic and Biomolecular Chemistry | 2017
    Co-auteur·e·s : Elisabetta Tobaldi - Igor Dovgan - Michel Mosser - Jean-Michel Becht - Alain Wagner
  • 2-(Maleimidomethyl)-1,3-Dioxanes (MD): a Serum-Stable Self-hydrolysable Hydrophilic Alternative to Classical Maleimide Conjugation, Scientific Reports | 2016
    Co-auteur·e·s : Igor Dovgan - Sergii Kolodych - Oleksandr Koniev - Alain Wagner
  • Copper-free click chemistry for microdroplet's W/O interface engineering, RSC Advances | 2016
    Co-auteur·e·s : Sylvain Ursuegui - Michel Mosser - Alain Wagner
  • From solution to in-cell study of the chemical reactivity of acid sensitive functional groups, Organic and Biomolecular Chemistry | 2016
    Co-auteur·e·s : Sylvain Jacques - Geoffray Leriche - Michel Mosser - Marc Nothisen - Christian Muller - Jean-Serge Remy - Alain Wagner
  • From solution to in-cell study of the chemical reactivity of acid sensitive functional groups: a rational approach towards improved cleavable linkers for biospecific endosomal release, Organic and Biomolecular Chemistry | 2016
    Co-auteur·e·s : Sylvain A. Jacques - Geoffray Leriche - Michel Mosser - Marc Nothisen - Christian Muller - Jean-serge Remy - Alain Wagner
  • Palladium‐Catalyzed Chemoselective and Biocompatible Functionalization of Cysteine‐Containing Molecules at Room Temperature, Chemistry - A European Journal | 2016
    Co-auteur·e·s : Riyadh Ahmed Atto Al‐Shuaeeb - Sergii Kolodych - Oleksandr Koniev - Sébastien Delacroix - Stéphane Erb - Stéphanie Nicolaÿ - Jean‐Christophe Cintrat - Jean‐Daniel Brion - Sarah Cianferani - Mouâd Alami - Alain Wagner - Samir Messaoudi
  • pH-Responsive Nanometric Polydiacetylenic Micelles Allow for Efficient Intracellular siRNA Delivery, ACS Applied Materials and Interfaces | 2016
    Co-auteur·e·s : Manon Ripoll - Patrick Neuberg - Antoine Kichler - Nassera Tounsi - Alain Wagner - Jean-Serge Remy
  • CBTF: New Amine-to-Thiol Coupling Reagent for Preparation of Antibody Conjugates with Increased Plasma Stability, Bioconjugate Chemistry | 2015
    Co-auteur·e·s : Sergii Kolodych - Oleksandr Koniev - Zoljargal Baatarkhuu - Jean-Yves Bonnefoy - Francois Debaene - Sarah Cianferani - Alain Van Dorsselaer - Alain Wagner
  • Development of models for prediction of the antioxidant activity of derivatives of natural compounds, Analytica Chimica Acta | 2015
    Co-auteur·e·s : Rok Martinčič - Igor Kuzmanovski - Alain Wagner - Marjana Novič
  • Developments and recent advancements in the field of endogenous amino acid selective bond forming reactions for bioconjugation., Chemical Society reviews | 2015
    Co-auteur·e·s : Oleksandr Koniev - Alain Wagner
  • Discovery of Potent Inhibitors of Schistosoma mansoni NAD(+) Catabolizing Enzyme, Journal of Medicinal Chemistry | 2015
    Co-auteur·e·s : Sylvain Jacques - Isabelle Kuhn - Oleksandr Koniev - Francis Schuber - Frances E. Lund - Alain Wagner - Hélène Muller-Steffner - Esther Kellenberger
  • MAPN: First-in-Class Reagent for Kinetically Resolved Thiol-to-Thiol Conjugation, Bioconjugate Chemistry | 2015
    Co-auteur·e·s : Oleksandr Koniev - Sergii Kolodych - Zoljargal Baatarkhuu - Johann Stojko - Jitka Eberova - Jean-Yves Bonnefoy - Sarah Cianferani - Alain Van Dorsselaer - Alain Wagner
  • Mannoside Glycolipid Conjugates Display Anti-inflammatory Activity by Inhibition of Toll-like Receptor-4 Mediated Cell Activation, ACS Chemical Biology | 2015
    Co-auteur·e·s : Vincent Flacher - Patrick Neuberg - Floriane Point - François Daubeuf - Quentin Muller - David Sigwalt - Jean-Daniel Fauny - Jean-Serge Remy - Nelly Frossard - Alain Wagner - Christopher G Mueller - Evelyne Schaeffer
  • Photopolymerized micelles of diacetylene amphiphile: physical characterization and cell delivery properties, Chemical Communications | 2015
    Co-auteur·e·s : Patrick Neuberg - Aurelia Perino - Emmanuelle Morin-Picardat - Nicolas Anton - Zeinab Darwich - Denis Weltin - Yves Mely - Andrey Klymchenko - Jean-Serge Remy - Alain Wagner
  • Spiro Diorthoester (SpiDo), a Human Plasma Stable Acid-Sensitive Cleavable Linker for Lysosomal Release, Bioconjugate Chemistry | 2015
    Co-auteur·e·s : Geoffray Leriche - Marc Nothisen - Nadege Baumlin - Christian Muller - Dominique Bagnard - Jean-Serge Remy - Sylvain Jacques - Alain Wagner
  • 4-Halogeno-sydnones for fast strain promoted cycloaddition with bicyclo- 6.1.0 -nonyne, Chemical Communications | 2014
    Co-auteur·e·s : Lucie Plougastel - Oleksandr Koniev - Simon Specklin - Elodie Decuypere - Christophe Creminon - David-Alexandre Buisson - Alain Wagner - Sergii Kolodych - Frederic Taran
  • Bio-specific and bio-orthogonal chemistries to switch-off the quencher of a FRET-based fluorescent probe: application to living-cell biothiol imaging, Chemical Communications | 2014
    Co-auteur·e·s : Coraline Egloff - Sylvain Jacques - Marc Nothisen - D Weltin - C Calligaro - Michel Mosser - Jean-Serge Remy - Alain Wagner
  • Copper-Chelating Azides for Efficient Click Conjugation Reactions in Complex Media, Angewandte Chemie International Edition | 2014
    Co-auteur·e·s : Valentina Bevilacqua - Mathias King - Manon Chaumontet - Marc Nothisen - Sandra Gabillet - David Buisson - Celine Puente - Alain Wagner - Frederic Taran
  • Developments in the Field of Bioorthogonal Bond Forming Reactions-Past and Present Trends, Bioconjugate Chemistry | 2014
    Co-auteur·e·s : Mathias King - Alain Wagner
  • Selective Irreversible Chemical Tagging of Cysteine with 3-Arylpropiolonitriles, Bioconjugate Chemistry | 2014
    Co-auteur·e·s : Oleksandr Koniev - Geoffray Leriche - Marc Nothisen - Jean-Serge Remy - Jean Marc Strub - Christine Schaeffer-Reiss - Alain Van Dorsselaer - Rachid Baati - Alain Wagner
  • A new series of Cs+, K+ and Na+ chelators: Synthesis, kinetics, thermodynamics and modeling, Inorganica Chimica Acta | 2013
    Co-auteur·e·s : Alexandre Korovitch - Antoine Le Roux - Florent Barbault - Miryana Hemadi - Nguyet-Thanh Ha-Duong - Claude Lion - Alain Wagner - Jean-Michel Chahine
  • Dynamic Micelles of Mannoside Glycolipids are more Efficient than Polymers for Inhibiting HIV-1 trans-Infection, Bioconjugate Chemistry | 2013
    Co-auteur·e·s : Evelyne Schaeffer - Laure Dehuyser - David Sigwalt - Vincent Flacher - Serena Bernacchi - Olivier Chaloin - Jean-Serge Remy - Christopher G Mueller - Rachid Baati - Alain Wagner
  • Dynamic Micelles of Mannoside Glycolipids are more Efficient than Polymers for Inhibiting HIV-1 trans-infection., Bioconjugate Chemistry | 2013
    Co-auteur·e·s : Evelyne Schaeffer - Laure Dehuyser - David Sigwalt - Vincent Flacher - Serena Bernacchi - Olivier Chaloin - Jean-Serge Remy - Christopher G Mueller - Rachid Baati - Alain Wagner
  • A FRET-based probe with a chemically deactivatable quencher, Chemical Communications | 2012
    Co-auteur·e·s : Geoffray Leriche - Ghyslain Budin - Zeinab Darwich - Denis Weltin - Yves Mely - Andrey Klymchenko - Alain Wagner
  • Capillary electrophoresis-inductively coupled plasma-mass spectrometry hyphenation for the determination at the nanogram scale of metal affinities and binding constants of phosphorylated ligands, Journal of Chromatography A | 2012
    Co-auteur·e·s : Fanny Varenne - Melanie Bourdillon - Michel Meyer - Yi Lin - Marie Brellier - Rachid Baati - Loic Charbonniere - Alain Wagner - Eric Doris - Frederic Taran - Agnes Hagege
  • Cleavable linkers in chemical biology, Bioorganic and Medicinal Chemistry | 2012
    Co-auteur·e·s : Geoffray Leriche - Louise Chisholm - Alain Wagner
  • First steps towards conformationally selective artificial lectins: the chair-boat discrimination by molecularly imprinted polymers, Chemical Communications | 2012
    Co-auteur·e·s : Vincent de Talance - Olivier Massinon - Rachid Baati - Alain Wagner - Stephane Vincent
  • New tetramethylthiepinium (TMTI) for copper-free click chemistry, Chemical Communications | 2012
    Co-auteur·e·s : Mathias King - Rachid Baati - Alain Wagner
  • Synthesis of Novel Mannoside Glycolipid Conjugates for Inhibition of HIV-1 Trans-Infection, Bioconjugate Chemistry | 2012
    Co-auteur·e·s : Laure Dehuyser - Evelyne Schaeffer - Olivier Chaloin - Christopher G Mueller - Rachid Baati - Alain Wagner
  • Towards a KCC2 blocker pharmacophore model, Bioorganic and Medicinal Chemistry Letters | 2012
    Co-auteur·e·s : Florence Lebon - Cecile Pegurier - Marie Ledecq - Benoit Mathieu - Nathalie Bosman - Anne Frycia - Sebastien Lengele - Kashinath Dhurke - Ananda Kanduluru - Stephane Meunier - Alain Wagner - Christian Wolff - Laurent Provins
  • Trimethoxyarene as a Highly Ionizable Tag for Reaction Analysis by Atmospheric Pressure Photoionization Mass Spectrometry (APPI/MS): Exploration of Heterocyclic Synthesis, European Journal of Organic Chemistry | 2012
    Co-auteur·e·s : Thuong Mathieu Bui The - Cedric Catala - Cyril Colas - Christine Schaeffer - Alain Van Dorsselaer - Andre Mann - Alain Wagner
  • Cationic Cyclization of 2-Alkenyl-1,3-dithiolanes: Diastereoselective Synthesis of trans-Decalins, Journal of Organic Chemistry | 2011
    Co-auteur·e·s : Sylvie Goncalves - Stefano Santoro - Marc Nicolas - Alain Wagner - Philippe Maillos - Fahmi Himo - Rachid Baati
  • Cationic Polydiacetylene Micelles for Gene Delivery, Bioconjugate Chemistry | 2011
    Co-auteur·e·s : Emmanuelle Morin - Marc Nothisen - Alain Wagner - Jean-Serge Remy
  • Design and Synthesis of New Antioxidants Predicted by the Model Developed on a Set of Pulvinic Acid Derivatives, Journal of Chemical Information and Modeling | 2011
    Co-auteur·e·s : Antoine Le Roux - Igor Kuzmanovski - Damien Habrant - Stephane Meunier - Pierre Bischoff - Brice Nadal - Sophie Thetiot-Laurent - Thierry Le Gall - Alain Wagner - Marjana Novic
  • Design, synthesis and evaluation of new alpha-nucleophiles for the hydrolysis of organophosphorus nerve agents: application to the reactivation of phosphorylated acetylcholinesterase, Tetrahedron | 2011
    Co-auteur·e·s : Geraldine Saint-Andre - Maria Kliachyna - Sanjeevarao Kodepelly - Ludivine Louise-Leriche - Emilie Gillon - Pierre-Yves Renard - Florian Nachon - Rachid Baati - Alain Wagner
  • First efficient uncharged reactivators for the dephosphylation of poisoned human acetylcholinesterase, Chemical Communications | 2011
    Co-auteur·e·s : Guillaume Mercey - Tristan Verdelet - Geraldine Saint-Andre - Emilie Gillon - Alain Wagner - Rachid Baati - Ludovic Jean - Florian Nachon - Pierre-Yves Renard
  • Mild chemo-selective hydration of terminal alkynes catalysed by AgSbF6, Chemical Communications | 2011
    Co-auteur·e·s : Mathieu Bui The Thuong - Andre Mann - Alain Wagner
  • Programmed Dispersions of MWNTs in Aqueous Media by Coating with Photopolymerizable Synthetic Amphiphiles, Journal of Physical Chemistry C | 2011
    Co-auteur·e·s : Cedric Thauvin - Aurelia Perino - Emmanuel Contal - Emmanuelle Morin - Patrick Schultz - Stephane Meunier - Alain Wagner
  • Self-Assembled Nanotubes and Helical Tapes from Diacetylene Nonionic Amphiphiles. Structural Studies before and after Polymerization, Langmuir | 2011
    Co-auteur·e·s : Aurelia Perino - Marc Schmutz - Stephane Meunier - Philippe Mesini - Alain Wagner
  • Stereoselective Addition of Grignard Reagents to New P-Chirogenic N-Phosphinoylbenzaldimines: Effect of the Phosphorus Substituents on the Stereoselectivity, European Journal of Organic Chemistry | 2011
    Co-auteur·e·s : Irene Notar Francesco - Coraline Egloff - Alain Wagner - Francoise Colobert
  • Synthesis and Radioprotective Properties of Pulvinic Acid Derivatives, ChemMedChem | 2011
    Co-auteur·e·s : Antoine Le Roux - Stephane Meunier - Thierry Le Gall - Jean-Marc Denis - Pierre Bischoff - Alain Wagner
  • A chemical labeling strategy for proteomics under nondenaturing conditions, ChemBioChem | 2010
    Co-auteur·e·s : Ghyslain Budin - Martin Moune Dimala - Valérie Lamour - Pierre Oudet - Charles Mioskowski - Stephane Meunier - Laurent Brino - Alain Wagner
  • Fine-Tuning the Morphology of Self-Assembled Nanostructures of Propargyl Ammonium-Based Amphiphiles, The Journal of Physical Chemistry B | 2010
    Co-auteur·e·s : Emmanuelle Morin - Jean-Michel Guenet - David D. Díaz - Jean-Serge Remy - Alain Wagner
  • Nondenaturing chemical proteomics for protein complex isolation and identification, ChemBioChem | 2010
    Co-auteur·e·s : Ghyslain Budin - Martin Moune-Dimala - Geoffray Leriche - Jean-Michel Saliou - Julie Papillon - Sarah Sanglier-Cianferani - Alain Van Dorsselaer - Valérie Lamour - Laurent Brino - Alain Wagner
  • Structure and behavior of polydiacetylene-based micelles, Macromolecular Chemistry and Physics | 2010
    Co-auteur·e·s : Aurélia Perino - Andrey Klymchenko - Alexandre Morere - Emmanuel Contal - Alain Rameau - Jean-Michel Guenet - Yves Mély - Alain Wagner
  • Structure-activity relationship study of betulinic acid, a novel and selective TGR5 agonist, and its synthetic derivatives: potential impact in diabetes, Journal of Medicinal Chemistry | 2010
    Co-auteur·e·s : Cédric Genet - Axelle Strehle - Céline Schmidt - Geoffrey Boudjelal - Annelise Lobstein - Kristina Schoonjans - Michel Souchet - Johan Auwerx - Régis Saladin - Alain Wagner
  • Tailoring drug release profile of low-molecular-weight hydrogels by supramolecular co-assembly and thiol-ene orthogonal coupling, Journal of Materials Chemistry | 2010
    Co-auteur·e·s : David Diaz - Emmanuelle Morin - Eva Schoen - Ghyslain Budin - Alain Wagner - Jean-Serge Remy

Conférences

  • Identification and structural studies of human DNA topoisomerases cellular complexes targeted by cancer drugs, Febs Journal | 2014
    Co-auteur·e·s : C Bedez - C Batisse - J Menetret - M Recher - Alain Wagner - V Lamour
  • A REPRESENTATION TO APPLY USUAL DATA MINING TECHNIQUES TO CHEMICAL REACTIONS - ILLUSTRATION ON THE RATE CONSTANT OF S(N)2 REACTIONS IN WATER, International Journal on Artificial Intelligence Tools | 2011
    Co-auteur·e·s : Frank Hoonakker - Nicolas Lachiche - Alexandre Varnek - Alain Wagner
  • Structure/function studies of DNA gyrase supramolecular complexes, Febs Journal | 2011
    Co-auteur·e·s : Julie Papillon - Noëlle Potier - Corinne Crucifix - Jean-François Ménétret - Cyriaque Genet - Emmanuelle Leize-Wagner - Pierre Oudet - Alain Wagner - Patrick Schultz - Valérie Lamour

Dr. Guilhem Chaubet

 chaubet[a]unistra.fr

 +33 (0)3 68 85 42 95


Dr. Alain Wagner

 alwag[at]unistra.fr

 +33 (0)3 68 85 41 97

News

[Translate to English:] schéma de synthèse
Team ICE

Preprint

The preprint submitted by the Ion Channel Engineering (ICE) team, in collaboration with the Smart NanoParticles (SNP) team, the UMR 5297, and the UPR…

Live SMLM
Team CPS

Publication

The CPS team has just published an article in Angewandte Chemie (Wiley) unveiling a new concept that enables the blinking of fluorescent probes for…

Figure
Team CPS

Publication

The CSP team has published a communication in ChemComm (RSC) on spontaneously blinking probes for super-resolution imaging of the plasma membrane. …

Certificate
Team BFC

Award

Guilhem Chaubet has just been awarded the Most Cited Publication of 2023 prize by "Chemistry: A European Journal." Congratulations! Article …

Jean-Marie Lehn foundation
Team CPS

Jean-Marie Lehn foundation: installation

The Chemistry of Photoresponsive Systems (CPS) team has received a support grant from the Jean-Marie Lehn Foundation for its recent establishment. …

microphone
Team BFC

Radiophonic broadcast

Radio cast with Guilhem Chaubet

Yu Qiu
Team CPS

New PhD student

The CPS team is pleased to welcome Yu Qiu, who will be conducting her PhD on the synthesis and characterization of biocompatible polymers for…

Julia Fath
Team SNP

New post-doctorate

We are happy to welcome Dr Julia Fath as a postdoctoral researcher in the SNP group. She will work on the “CadoRNA” ANR project to develop Carbon…

France 2030
Team CPS

New chemistry postdoc

The CPS team is pleased to welcome Dr. Lucille Weiss as a postdoctoral researcher. She will be working on an IdEx “Attractivité” project aimed at…

Thèses et parenthèses
Team BFC

Publication of a graphic novel

Targeted cancer therapies

molecular rotor
Team CPS

Publication

The Chemistry of Photoresponsive Systems team has just published an article in Soft Matter (RSC) dedicated to the study of nano-emulsion viscosity. T…

French chemistry society
Team BFC

Nomination to the French Chemical Society | SCF

Guilhem Chaubet has just been nominated as a junior member of the French Chemical Society. Congratulations! BFC news

Colistine
Team CPS

Publication

Adjuvant-loaded nanoemulsion greatly enhanced antibiotic (colistin) efficacy.

piezo thesis
Team ICE

Funding

Thomas Grutter and Andrey Klymchenko (from UMR 7021) are recipients of the ITI NeuroStra call for projects "interdisciplinary PhD." The project will…

Saint Thomas Chapter
Team BFC

Distinction

Lorenzo Turelli, from the BFC team, is the laureate of the 2024 Saint Thomas Chapter Award. Congratulations! News BFC Interview

Events

[Translate to English:] JCI 2025

Illkirch campus days 2025

One and a half day of scientific meeting that bring together researchers from all the campus to learn, network and get creative. With: The…

26 27 May 2025
8h30 14h09
Pôle API, 67400 Illkirch-Graffenstaden
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Laboratoire de chémo-biologie synthétique et thérapeutique | CBST | UMR 7199


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