Thomas Grutter CV

Short biosketch

Thomas Grutter is Research Director at CNRS, Group Leader of the team ‘Ion Channel Engineering’, and Director of the CBST lab since January 1st, 2024. Between 2017 and 2023, he held the position of Deputy Director of the CAMB laboratory.

After studying chemistry and biology at the University of Strasbourg, he received his PhD degree in bio-organic chemistry under the supervision of Pr. Maurice Goeldner. Then, Thomas Grutter moved to the Pasteur Institute in Paris as a postdoctoral fellow in the lab of Pr. Jean-Pierre Changeux to work on structure-function of pentameric ligand-gated ion channels (LGICs), combining molecular biology, patch-clamp electrophysiology and modeling. In 2003, he obtained a permanent position at the CNRS and returned to Strasbourg in 2007 to establish his own research group.

Grutter’s research team is dedicated to investigating the biophysical and molecular aspects of trimeric ion channels and LGICs (PIEZO channels and P2X receptors) using tools from chemical biology. He has supervised over a dozen PhD students and postdoctoral fellows. Notably, his lab pioneered the development of the first light-gated P2X receptors using chemical photoswitches, for which Thomas Grutter was awarded the ‘Prix de la Recherche’ in Chemistry in 2014. More recently, his research has focused on the development of the first light-gated PIEZO channels. Thomas Grutter is also a 2019 USIAS fellow.

 

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