79 publications disponibles
Articles scientifiques
- Supramolecular Bioconjugation Strategy for Antibody-Targeted Delivery of siRNA, Bioconjugate Chemistry | 2024
Co-auteur(s) : Manon Ripoll - Heloise Cahuzac - Igor Dovgan - Sylvain Ursuegui - Patrick Neuberg - Stéphane Erb - Sarah Cianferani - Antoine Kichler - Jean-Serge Remy - Alain Wagner - Microglial P2X4 receptors are essential for spinal neurons hyperexcitability and tactile allodynia in male and female neuropathic mice, iScience | 2023
Co-auteur(s) : Damien Gilabert - Alexia Duveau - Sara Carracedo - Nathalie Linck - Adeline Langla - Rieko Muramatsu - Friedrich Koch-Nolte - François Rassendren - Thomas Grutter - Pascal Fossat - Eric Boué-Grabot - Lauriane Ulmann - Optical control of PIEZO1 channels, Nature Communications | 2023
Co-auteur(s) : Francisco Andrés Peralta - Melaine Balcon - Adeline Martz - Deniza Biljali - Federico Cevoli - Benoit Arnould - Antoine Taly - Thierry Chataigneau - Thomas Grutter - Untangling Macropore Formation and Current Facilitation in P2X7, International Journal of Molecular Sciences | 2023
Co-auteur(s) : Federico Cevoli - Benoit Arnould - Francisco Andrés Peralta - Thomas Grutter - Comparing transmembrane protein structures with ATOLL, Bioinformatics | 2021
Co-auteur(s) : Célien Jacquemard - Guillaume Bret - Thomas Grutter - Esther Kellenberger - P2X7 Receptors and TMEM16 Channels Are Functionally Coupled with Implications for Macropore Formation and Current Facilitation, International Journal of Molecular Sciences | 2021
Co-auteur(s) : Kate Dunning - Adeline Martz - Francisco Andés Peralta - Federico Cevoli - Eric Boué-Grabot - Vincent Compan - Fanny Gautherat - Patrick Wolf - Thierry Chataigneau - Thomas Grutter - Photo-isomerizable tweezers to probe ionotropic receptor mechanisms, Current Opinion in Pharmacology | 2021
Co-auteur(s) : Laurie Peverini - Kate Dunning - Francisco Andres Peralta - Thomas Grutter - Update of P2X receptor properties and their pharmacology: IUPHAR Review 30, British Journal of Pharmacology | 2021
Co-auteur(s) : Peter Illes - Christa E. Müller - Kenneth A. Jacobson - Thomas Grutter - Annette Nicke - Samuel J. Fountain - Charles Kennedy - Günther Schmalzing - Michael F. Jarvis - Stanko S. Stojilkovic - Brian F. King - Francesco Di Virgilio - Dual Gene Delivery Reagents From Antiproliferative Alkylphospholipids for Combined Antitumor Therapy, Frontiers in Chemistry | 2020
Co-auteur(s) : Boris Gaillard - Jean-serge Remy - Francoise Pons-lebeau - Luc Lebeau - P2X-GCaMPs as Versatile Tools for Imaging Extracellular ATP Signaling, eneuro | 2020
Co-auteur(s) : Matthias Ollivier - Juline Beudez - Nathalie Linck - Thomas Grutter - Vincent Compan - Francois Rassendren - Synthesis and Evaluation of Antitumor Alkylphospholipid Prodrugs, Pharmaceutical Research | 2020
Co-auteur(s) : Boris Gaillard - Jean-serge Remy - Francoise Pons-lebeau - Luc Lebeau - Design and evaluation of ionizable peptide amphiphiles for siRNA delivery, International Journal of Pharmaceutics | 2019
Co-auteur(s) : Patrick Neuberg - Alain Wagner - Jean-Serge Remy - Antoine Kichler - Erufosine (ErPC3) Cationic Prodrugs as Dual Gene Delivery Reagents for Combined Antitumor Therapy, Chemistry – A European Journal | 2019
Co-auteur(s) : Boris Gaillard - Cendrine Seguin - Jean-Serge Remy - Françoise Pons - Luc Lebeau - Molecular determinants for agonist recognition and discrimination in P2X2 receptors, Journal of General Physiology | 2019
Co-auteur(s) : Federica Gasparri - Jesper Wengel - Thomas Grutter - Stephan A. Pless - Cationic Oligospermine-Oligonucleotide Conjugates Provide Carrier-free Splice Switching in Monolayer Cells and Spheroids, Molecular Therapy - Nucleic Acids | 2018
Co-auteur(s) : Marc Nothisen - Phanélie Perche-Létuvée - Jean-Paul Behr - Jean-Serge Remy - Mitsuharu Kotera - Co-delivery of anti-PLK-1 siRNA and camptothecin by nanometric polydiacetylenic micelles results in a synergistic cell killing, RSC Advances | 2018
Co-auteur(s) : Manon Ripoll - Marie Pierdant - Patrick Neuberg - Dominique Bagnard - Alain Wagner - Antoine Kichler - Jean-Serge Remy - New Insights Into Permeation of Large Cations Through ATP-Gated P2X Receptors, Frontiers in Molecular Neuroscience | 2018
Co-auteur(s) : Laurie Peverini - Juline Beudez - Kate Dunning - Thierry Chataigneau - Thomas Grutter - Polydiacetylenic nanofibers as new siRNA vehicles for in vitro and in vivo delivery, Nanoscale | 2018
Co-auteur(s) : Patrick Neuberg - Imene Hamaidi - Sabrina Danilin - Manon Ripoll - Veronique Lindner - Marc Nothisen - Alain Wagner - Antoine Kichler - Thierry Massfelder - Jean-Serge Remy - On the permeation of large organic cations through the pore of ATP-gated P2X receptors, Proceedings of the National Academy of Sciences | 2017
Co-auteur(s) : Mahboubi Harkat - Laurie Peverini - Adrien Cerdan - Kate Dunning - Juline Beudez - Adeline Martz - Nicolas Calimet - Alexandre Specht - Marco Cecchini - Thierry Chataigneau - Thomas Grutter - P2X2 Dominant Deafness Mutations Have No Negative Effect on Wild-Type Isoform: Implications for Functional Rescue and in Deafness Mechanism, Frontiers in Molecular Neuroscience | 2017
Co-auteur(s) : Yan Zhu - Juline Beudez - Ning Yu - Thomas Grutter - Hong-Bo Zhao - From solution to in-cell study of the chemical reactivity of acid sensitive functional groups, Organic and Biomolecular Chemistry | 2016
Co-auteur(s) : Sylvain Jacques - Geoffray Leriche - Michel Mosser - Marc Nothisen - Christian Muller - Jean-Serge Remy - Alain Wagner - From solution to in-cell study of the chemical reactivity of acid sensitive functional groups: a rational approach towards improved cleavable linkers for biospecific endosomal release, Organic and Biomolecular Chemistry | 2016
Co-auteur(s) : Sylvain A. Jacques - Geoffray Leriche - Michel Mosser - Marc Nothisen - Christian Muller - Jean-serge Remy - Alain Wagner - Molecular structure and function of P2X receptors, Neuropharmacology | 2016
Co-auteur(s) : Chloé Habermacher - Kate Dunning - Thierry Chataigneau - Thomas Grutter - Photo-switchable tweezers illuminate pore-opening motions of an ATP-gated P2X ion channel, eLife | 2016
Co-auteur(s) : Chloé Habermacher - Adeline Martz - Nicolas Calimet - Damien Lemoine - Laurie Peverini - Alexandre Specht - Marco Cecchini - Thomas Grutter - Preparation of poly(ethylene imine) derivatives with precisely controlled molecular weight, European Polymer Journal | 2016
Co-auteur(s) : Matthieu Landa - Mitsuharu Kotera - Jean-Serge Remy - Nezha Badi - Structure Tuning of Cationic Oligospermine–siRNA Conjugates for Carrier-Free Gene Silencing, Molecular Pharmaceutics | 2016
Co-auteur(s) : Marc Nothisen - Jérémy Bagilet - Jean-Paul Behr - Jean-Serge Remy - Mitsuharu Kotera - Synthesis of giant globular multivalent glycofullerenes as potent inhibitors in a model of Ebola virus infection, Nature Chemistry | 2016
Co-auteur(s) : Antonio Munoz - David Sigwalt - Beatriz Illescas - Joanna Luczkowiak - Laura Rodriguez-Perez - Iwona Nierengarten - Michel Holler - Jean-serge Remy - Kevin Buffet - Stéphane Vincent - Javier Rojo - Rafael Delgado - Jean-françois Nierengarten - Nazario Martin - pH-Responsive Nanometric Polydiacetylenic Micelles Allow for Efficient Intracellular siRNA Delivery, ACS Applied Materials and Interfaces | 2016
Co-auteur(s) : Manon Ripoll - Patrick Neuberg - Antoine Kichler - Nassera Tounsi - Alain Wagner - Jean-Serge Remy - Architectural and Functional Similarities between Trimeric ATP-Gated P2X Receptors and Acid-Sensing Ion Channels, Journal of Molecular Biology | 2015
Co-auteur(s) : Stephan Kellenberger - Thomas Grutter - Mannoside Glycolipid Conjugates Display Anti-inflammatory Activity by Inhibition of Toll-like Receptor-4 Mediated Cell Activation, ACS Chemical Biology | 2015
Co-auteur(s) : Vincent Flacher - Patrick Neuberg - Floriane Point - François Daubeuf - Quentin Muller - David Sigwalt - Jean-Daniel Fauny - Jean-Serge Remy - Nelly Frossard - Alain Wagner - Christopher G Mueller - Evelyne Schaeffer - Photopolymerized micelles of diacetylene amphiphile: physical characterization and cell delivery properties, Chemical Communications | 2015
Co-auteur(s) : Patrick Neuberg - Aurelia Perino - Emmanuelle Morin-Picardat - Nicolas Anton - Zeinab Darwich - Denis Weltin - Yves Mely - Andrey Klymchenko - Jean-Serge Remy - Alain Wagner - Spiro Diorthoester (SpiDo), a Human Plasma Stable Acid-Sensitive Cleavable Linker for Lysosomal Release, Bioconjugate Chemistry | 2015
Co-auteur(s) : Geoffray Leriche - Marc Nothisen - Nadege Baumlin - Christian Muller - Dominique Bagnard - Jean-Serge Remy - Sylvain Jacques - Alain Wagner - Bio-specific and bio-orthogonal chemistries to switch-off the quencher of a FRET-based fluorescent probe: application to living-cell biothiol imaging, Chemical Communications | 2014
Co-auteur(s) : Coraline Egloff - Sylvain Jacques - Marc Nothisen - D Weltin - C Calligaro - Michel Mosser - Jean-Serge Remy - Alain Wagner - Selective Irreversible Chemical Tagging of Cysteine with 3-Arylpropiolonitriles, Bioconjugate Chemistry | 2014
Co-auteur(s) : Oleksandr Koniev - Geoffray Leriche - Marc Nothisen - Jean-Serge Remy - Jean Marc Strub - Christine Schaeffer-Reiss - Alain Van Dorsselaer - Rachid Baati - Alain Wagner - Cell-penetrating cationic siRNA and lipophilic derivatives efficient at nanomolar concentrations in the presence of serum and albumin, Journal of Controlled Release | 2013
Co-auteur(s) : Phanelie Perche - Marc Nothisen - Jeremy Bagilet - Jean-Paul Behr - Mitsuharu Kotera - Jean-Serge Remy - Do iodinated nano-emulsions designed for preclinical vascular imaging alter the vascular reactivity in rat aorta?, International Journal of Pharmaceutics | 2013
Co-auteur(s) : Nicolas Anton - Marina Atzenhoffer - Francois Daubeuf - Xiang Li - Valerie Schini-kerth - Barbara Delmotte - Thierry Vandamme - Thierry Chataigneau - Dynamic Micelles of Mannoside Glycolipids are more Efficient than Polymers for Inhibiting HIV-1 trans-Infection, Bioconjugate Chemistry | 2013
Co-auteur(s) : Evelyne Schaeffer - Laure Dehuyser - David Sigwalt - Vincent Flacher - Serena Bernacchi - Olivier Chaloin - Jean-Serge Remy - Christopher G Mueller - Rachid Baati - Alain Wagner - Dynamic Micelles of Mannoside Glycolipids are more Efficient than Polymers for Inhibiting HIV-1 trans-infection., Bioconjugate Chemistry | 2013
Co-auteur(s) : Evelyne Schaeffer - Laure Dehuyser - David Sigwalt - Vincent Flacher - Serena Bernacchi - Olivier Chaloin - Jean-Serge Remy - Christopher G Mueller - Rachid Baati - Alain Wagner - Endothelium-independent and endothelium-dependent vasorelaxation by a dichloromethane fraction from Anogeissus Leiocarpus (DC) Guill. Et Perr. (Combretaceae): possible involvement of cyclic nucleotide phosphodiesterase inhibition, African Journal of Traditional Complementary and Alternative Medicines | 2013
Co-auteur(s) : Lazare Belemnaba - Sylvin Ouedraogo - Cyril Auger - Thierry Chataigneau - Aristide Traore - Innocent Guissou - Claire Lugnier - Valerie Schini-Kerth - Bernard Bucher - Exploring the ATP-binding site of P2X receptors, Frontiers in Cellular Neuroscience | 2013
Co-auteur(s) : Thierry Chataigneau - Damien Lemoine - Thomas Grutter - Moving through the gate in ATP-activated P2X receptors, Trends in Biochemical Sciences | 2013
Co-auteur(s) : Ruotian Jiang - Antoine Taly - Thomas Grutter - Optical control of an ion channel gate, Proceedings of the National Academy of Sciences of the United States of America | 2013
Co-auteur(s) : Damien Lemoine - Chloe Habermacher - Adeline Martz - Pierre-Francois Mery - Nathalie Bouquier - Fanny Diverchy - Antoine Taly - Francois Rassendren - Alexandre Specht - Thomas Grutter - Polycationic Pillar 5 arene Derivatives: Interaction with DNA and Biological Applications, Chemistry - A European Journal | 2013
Co-auteur(s) : Iwona Nierengarten - Marc Nothisen - David Sigwalt - Thomas Biellmann - Michel Holler - Jean-Serge Remy - Jean-Francois Nierengarten - Grape-derived polyphenols improve aging-related endothelial dysfunction in rat mesenteric artery: role of oxidative stress and the angiotensin system, PLoS ONE | 2012
Co-auteur(s) : Noureddine Idris Khodja - Thierry Chataigneau - Cyril Auger - Valerie Schini-Kerth - Intermediate closed channel state(s) precede(s) activation in the ATP-gated P2X2 receptor, Channels | 2012
Co-auteur(s) : Ruotian Jiang - Antoine Taly - Damien Lemoine - Adeline Martz - Alexandre Specht - Thomas Grutter - Involvement of the cysteine-rich head domain in activation and desensitization of the P2X1 receptor, Proceedings of the National Academy of Sciences of the United States of America | 2012
Co-auteur(s) : Eva Loerinczi - Yogesh Bhargava - Stephen Marino - Antoine Taly - Karina Kaczmarek-Hajek - Alonso Barrantes-Freer - Sebastien Dutertre - Thomas Grutter - Juergen Rettinger - Annette Nicke - Ligand-Gated Ion Channels: New Insights into Neurological Disorders and Ligand Recognition, Chemical Reviews | 2012
Co-auteur(s) : Damien Lemoine - Ruotian Jiang - Antoine Taly - Thierry Chataigneau - Alexandre Specht - Thomas Grutter - Molecular mechanisms of the cardiovascular protective effects of polyphenols, British Journal of Nutrition | 2012
Co-auteur(s) : Ramaroson Andriantsitohaina - Cyril Auger - Thierry Chataigneau - Nelly Etienne-selloum - Huige Li - M Martinez - Valerie Schini-kerth - Ismail Laher - Natural product extract of Dicksonia sellowiana induces endothelium-dependent relaxations by a redox-sensitive Src- and Akt-dependent activation of eNOS in porcine coronary arteries, Journal of Vascular Research | 2012
Co-auteur(s) : Yanna Rattmann - Eric Anselm - Jong-Hun Kim - Stéphanie Dal-Ros - Cyril Auger - Obdulio G Miguel - Adair R Santos - Thierry Chataigneau - Valérie Schini-kerth - Tightening of the ATP-binding sites induces the opening of P2X receptor channels, EMBO Journal | 2012
Co-auteur(s) : Ruotian Jiang - Antoine Taly - Damien Lemoine - Adeline Martz - Olivier Cunrath - Thomas Grutter - Agonist trapped in ATP-binding sites of the P2X2 receptor, Proceedings of the National Academy of Sciences of the United States of America | 2011
Co-auteur(s) : Ruotian Jiang - Damien Lemoine - Adeline Martz - Antoine Taly - Sophie Gonin - Lia de Carvalho - Alexandre Specht - Thomas Grutter - Cationic Polydiacetylene Micelles for Gene Delivery, Bioconjugate Chemistry | 2011
Co-auteur(s) : Emmanuelle Morin - Marc Nothisen - Alain Wagner - Jean-Serge Remy - From Toxins Targeting Ligand Gated Ion Channels to Therapeutic Molecules, Toxins | 2011
Co-auteur(s) : Adak Nasiripourdori - Valerie Taly - Thomas Grutter - Antoine Taly - Fruit juice-induced endothelium-dependent relaxations in isolated porcine coronary arteries: evaluation of different fruit juices and purees and optimization of a red fruit juice blend, Food & function | 2011
Co-auteur(s) : Cyril Auger - Jong-Hun Kim - Sandrine Trinh - Thierry Chataigneau - A Popken - Valérie Schini-kerth - Gene delivery with polycationic fullerene hexakis-adducts, Chemical Communications | 2011
Co-auteur(s) : David Sigwalt - Michel Holler - Julien Iehl - Jean-françois Nierengarten - Marc Nothisen - Emmanuelle Morin - Jean-Serge Remy - MMT, Npeoc-protected spermine, a valuable synthon for the solid phase synthesis of oligonucleotide oligospermine conjugates via guanidine linkers, Bioorganic and Medicinal Chemistry | 2011
Co-auteur(s) : Phanelie Perche - Mitsuharu Kotera - Jean-Serge Remy - Retrochalcone derivatives are positive allosteric modulators at synaptic and extrasynaptic GABA(A) receptors in vitro, British Journal of Pharmacology | 2011
Co-auteur(s) : Ruotian Jiang - Akiko Miyamoto - Adeline Martz - Alexandre Specht - Hitoshi Ishibashi - Marie Kueny-Stotz - Stefan Chassaing - Raymond Brouillard - Lia de Carvalho - Maurice Goeldner - Junichi Nabekura - Mogens Nielsen - Thomas Grutter - Vascular Protection by Natural Product-Derived Polyphenols: In Vitro and In Vivo Evidence, Planta Medica | 2011
Co-auteur(s) : Valerie Schini-Kerth - Nelly Etienne-Selloum - Thierry Chataigneau - Cyril Auger - A Putative Extracellular Salt Bridge at the Subunit Interface Contributes to the Ion Channel Function of the ATP-gated P2X2 Receptor, Journal of Biological Chemistry | 2010
Co-auteur(s) : Ruotian Jiang - Adeline Martz - Sophie Gonin - Antoine Taly - Lia Prado De Carvalho - Thomas Grutter - Adenovirus-derived vectors for prostate cancer gene therapy., Human Gene Therapy | 2010
Co-auteur(s) : J de Vrij - R Willemsen - L Lindholm - R Hoeben - G Consortium - C Bangma - C Barber - J Behr - S Briggs - R Carlisle - W Cheng - I Dautzenberg - C de Ridder - H Dzojic - P Erbacher - M Essand - K Fisher - A Frazier - L Georgopoulos - I Jennings - S Kochanek - D Koppers-Lalic - R Kraaij - F Kreppel - M Magnusson - N Maitland - P Neuberg - R Nugent - M Ogris - Jean-Serge Remy - M Scaife - E Schenk-Braat - E Schooten - L Seymour - M Slade - P Szyjanowicz - T Totterman - T Uil - K Ulbrich - L van der Weel - W van Weerden - E Wagner - G Zuber - Fine-Tuning the Morphology of Self-Assembled Nanostructures of Propargyl Ammonium-Based Amphiphiles, The Journal of Physical Chemistry B | 2010
Co-auteur(s) : Emmanuelle Morin - Jean-Michel Guenet - David D. Díaz - Jean-Serge Remy - Alain Wagner - Proton Sponge Trick for pH-Sensitive Disassembly of Polyethylenimine-Based siRNA Delivery Systems, Bioconjugate Chemistry | 2010
Co-auteur(s) : Gaelle Creusat - Anne-Sophie Rinaldi - Etienne Weiss - Rkia Elbaghdadi - Jean-Serge Remy - Rita Mulherkar - Guy Zuber - Tailoring drug release profile of low-molecular-weight hydrogels by supramolecular co-assembly and thiol-ene orthogonal coupling, Journal of Materials Chemistry | 2010
Co-auteur(s) : David Diaz - Emmanuelle Morin - Eva Schoen - Ghyslain Budin - Alain Wagner - Jean-Serge Remy - Cationic siRNAs Provide Carrier-Free Gene Silencing in Animal Cells, Journal of the American Chemical Society | 2009
Co-auteur(s) : Marc Nothisen - Mitsuharu Kotera - Emilie Voirin - Jean-Serge Remy - Jean-Paul Behr - Zip Nucleic Acids: new high affinity oligonucleotides as potent primers for PCR and reverse transcription, Nucleic Acids Research | 2009
Co-auteur(s) : Valérie Moreau - Emilie Voirin - Clément Paris - Mitsuharu Kotera - Marc Nothisen - Jean-Serge Remy - Jean-Paul Behr - Patrick Erbacher - Nathalie Lenne-Samuel
Conférences
- New insights into P2X permeation | 2021
Co-auteur(s) : Thomas Grutter - Les cibles thérapeutiques de demain : de la structure moléculaire à la fonction | 2019
Co-auteur(s) : Thomas Grutter - Molecular engineering of ATP-gated P2X ion channels provides new insights into ion permeation and gating mechanisms | 2019
Co-auteur(s) : Thomas Grutter - Optical control of P2X receptors | 2019
Co-auteur(s) : Thomas Grutter - Permeation mechanisms of large cations in ATP-gated P2X ion channels | 2019
Co-auteur(s) : Thomas Grutter - Optical control of P2X receptors | 2018
Co-auteur(s) : Thomas Grutter - Opening of a P2X ion channel with light, Purinergic Signalling | 2014
Co-auteur(s) : Thomas Grutter - Optical dissection of gating in P2X receptors, Purinergic Signalling | 2014
Co-auteur(s) : Chloé Habermacher - Damien Lemoine - Adeline Martz - Alexandre Specht - Thomas Grutter - Optogating a powerful approach to control an ion-channel gate, Purinergic Signalling | 2014
Co-auteur(s) : Damien Lemoine - Chloe Habermacher - Adeline Martz - Pierre-Francois Mery - Nathalie Bouquier - Fanny Diverchy - Antoine Taly - Francois Rassendren - Alexandre Specht - Thomas Grutter - Grape-derived polyphenols persistently improve the aging-related endothelial dysfunction, particularly the edhf component, in the rat mesenteric artery: role of ros, skca, ikca and the angiotensin system, Journal of Vascular Research | 2012
Co-auteur(s) : Noureddine Idris Khodja - Thierry Chataigneau - Cyril Auger - Valerie Schini-Kerth
Parties d'ouvrages
- Manipulation of ion channel gating with photoswitchable tweezers., Methods in enzymology | 2021
Co-auteur(s) : Kate Dunning - Thomas Grutter - Cationic Photopolymerized Polydiacetylenic (PDA) Micelles for siRNA Delivery, Nanotechnology for Nucleic Acid Delivery | 2019
Co-auteur(s) : Manon Ripoll - Patrick Neuberg - Jean-Serge Remy - Antoine Kichler - P2X Receptors, Neuronal Ion Channels | 2018
Co-auteur(s) : Annette Nicke - Thomas Grutter - Terrance Egan
Productions de vulgarisation
- Des nanomachines photochimiques pour explorer le vivant | 2017
Co-auteur(s) : Thomas Grutter - Chloé Habermacher - Laurie Peverini