Publications

2023

  • Cevoli, F., Arnould, B., Peralta, F. A., Grutter, T. "Untangling Macropore Formation and Current Facilitation in P2X7," Int J Mol Sci, (2023) 24 (13). ( DOI: 10.3390/ijms241310896 ).
  • Peralta, F. A., Balcon, M., Martz, A., Biljali, D., Cevoli, F., Arnould, B., Taly, A., Chataigneau, T., Grutter, T. "Optical control of PIEZO1 channels," Nat Commun, (2023) 14 (1), 1269. ( DOI: 10.1038/s41467-023-36931-0).
  • Gilabert, D., Duveau, A., Carracedo, S., Linck, N., Langla, A., Muramatsu, R., Koch-Nolte, F., Rassendren, F., Grutter, T., Fossat, P., Boue-Grabot, E., Ulmann, L. "Microglial P2X4 receptors are essential for spinal neurons hyperexcitability and tactile allodynia in male and female neuropathic mice," iScience, (2023) 26 (11), 108110. ( DOI: 10.1016/j.isci.2023.108110 ).

2022

  • Peverini, L., Dunning, K., Peralta, F. A., Grutter, T. "Photo-isomerizable tweezers to probe ionotropic receptor mechanisms," Curr Opin Pharmacol, (2022) 62, 109-116. ( DOI: 10.1016/j.coph.2021.11.011 ).
  • Jacquemard, C., Bret, G., Grutter, T., Kellenberger, E. "Comparing transmembrane protein structures with ATOLL," Bioinformatics, (2022) 38 (6), 1743-1744. ( DOI: 10.1093/bioinformatics/btab860 ).
  • Dunning, K., Peverini, L., Grutter, T. "Using Symmetrical Organic Cation Solutions to Study P2X7 Ion Permeation," Methods Mol Biol, (2022) 2510, 239-252. ( DOI: 10.1007/978-1-0716-2384-8_12 ).

2021

  • Illes, P., Muller, C. E., Jacobson, K. A., Grutter, T., Nicke, A., Fountain, S. J., Kennedy, C., Schmalzing, G., Jarvis, M. F., Stojilkovic, S. S., King, B. F., Di Virgilio, F. "Update of P2X receptor properties and their pharmacology: IUPHAR Review 30," Br J Pharmacol, (2021) 178 (3), 489-514. ( DOI: 10.1111/bph.15299 ).
  • Ollivier, M., Beudez, J., Linck, N., Grutter, T., Compan, V., Rassendren, F. "P2X-GCaMPs as Versatile Tools for Imaging Extracellular ATP Signaling," eNeuro, (2021) 8 (1). ( DOI: 10.1523/ENEURO.0185-20.2020 ).
  • Dunning, K., Grutter, T. "Manipulation of ion channel gating with photoswitchable tweezers," Methods Enzymol, (2021) 653, 349-376. ( DOI: 10.1016/bs.mie.2020.12.021 ).
  • Dunning, K., Martz, A., Peralta, F. A., Cevoli, F., Boue-Grabot, E., Compan, V., Gautherat, F., Wolf, P., Chataigneau, T., Grutter, T. "P2X7 Receptors and TMEM16 Channels Are Functionally Coupled with Implications for Macropore Formation and Current Facilitation," Int J Mol Sci, (2021) 22 (12). ( DOI: 10.3390/ijms22126542 ).

2019

  • Gasparri, F., Wengel, J., Grutter, T., Pless, S. A. "Molecular determinants for agonist recognition and discrimination in P2X2 receptors," J Gen Physiol, (2019) 151 (7), 898-911. ( DOI: 10.1085/jgp.201912347 ).

2018

  • Peverini, L., Beudez, J., Dunning, K., Chataigneau, T., Grutter, T. "New Insights Into Permeation of Large Cations Through ATP-Gated P2X Receptors," Front Mol Neurosci, (2018) 11, 265. ( DOI: 10.3389/fnmol.2018.00265 ).

2017

  • Zhu, Y., Beudez, J., Yu, N., Grutter, T., Zhao, H. B. "P2X2 Dominant Deafness Mutations Have No Negative Effect on Wild-Type Isoform: Implications for Functional Rescue and in Deafness Mechanism," Front Mol Neurosci, (2017) 10, 371. ( DOI: 10.3389/fnmol.2017.00371 ).
  • Harkat, M., Peverini, L., Cerdan, A. H., Dunning, K., Beudez, J., Martz, A., Calimet, N., Specht, A., Cecchini, M., Chataigneau, T., Grutter, T. "On the permeation of large organic cations through the pore of ATP-gated P2X receptors," Proc Natl Acad Sci U S A, (2017) 114 (19), E3786-E3795. ( DOI: 10.1073/pnas.1701379114 ).

2016

  • Habermacher, C., Dunning, K., Chataigneau, T., Grutter, T. "Molecular structure and function of P2X receptors," Neuropharmacology, (2016) 104, 18-30. ( DOI: 10.1016/j.neuropharm.2015.07.032 ).
  • Habermacher, C., Martz, A., Calimet, N., Lemoine, D., Peverini, L., Specht, A., Cecchini, M., Grutter, T. "Photo-switchable tweezers illuminate pore-opening motions of an ATP-gated P2X ion channel," Elife, (2016) 5, e11050. ( DOI: 10.7554/eLife.11050 ).

2015

  • Kellenberger, S., Grutter, T. "Architectural and functional similarities between trimeric ATP-gated P2X receptors and acid-sensing ion channels," J Mol Biol, (2015) 427 (1), 54-66. ( DOI: 10.1016/j.jmb.2014.06.004 ).

2013

  • Jiang, R., Taly, A., Grutter, T. "Moving through the gate in ATP-activated P2X receptors," Trends Biochem Sci, (2013) 38 (1), 20-29. ( DOI: 10.1016/j.tibs.2012.10.006 ).
  • Chataigneau, T., Lemoine, D., Grutter, T. "Exploring the ATP-binding site of P2X receptors," Front Cell Neurosci, (2013) 7, 273. ( DOI: 10.3389/fncel.2013.00273 ).
  • Lemoine, D., Habermacher, C., Martz, A., Mery, P. F., Bouquier, N., Diverchy, F., Taly, A., Rassendren, F., Specht, A., Grutter, T. "Optical control of an ion channel gate," Proc Natl Acad Sci U S A, (2013) 110 (51), 20813-20818. ( DOI: 10.1073/pnas.1318715110 ).

2012

  • Jiang, R., Taly, A., Lemoine, D., Martz, A., Cunrath, O., Grutter, T. "Tightening of the ATP-binding sites induces the opening of P2X receptor channels," EMBO J, (2012) 31 (9), 2134-2143. ( DOI: 10.1038/emboj.2012.75 ).
  • Lorinczi, E., Bhargava, Y., Marino, S. F., Taly, A., Kaczmarek-Hajek, K., Barrantes-Freer, A., Dutertre, S., Grutter, T., Rettinger, J., Nicke, A. "Involvement of the cysteine-rich head domain in activation and desensitization of the P2X1 receptor," Proc Natl Acad Sci U S A, (2012) 109 (28), 11396-11401. ( DOI: 10.1073/pnas.1118759109 ).
  • Lemoine, D., Jiang, R., Taly, A., Chataigneau, T., Specht, A., Grutter, T. "Ligand-gated ion channels: new insights into neurological disorders and ligand recognition," Chem Rev, (2012) 112 (12), 6285-6318. ( DOI: 10.1021/cr3000829 ).
  • Jiang, R., Taly, A., Lemoine, D., Martz, A., Specht, A., Grutter, T. "Intermediate closed channel state(s) precede(s) activation in the ATP-gated P2X2 receptor," Channels (Austin), (2012) 6 (5), 398-402. ( DOI: 10.4161/chan.21520 ).

2011

  • Nasiripourdori, A., Taly, V., Grutter, T., Taly, A. "From toxins targeting ligand gated ion channels to therapeutic molecules," Toxins (Basel), (2011) 3 (3), 260-293. ( DOI: 10.3390/toxins3030260 ).
  • Jiang, R., Lemoine, D., Martz, A., Taly, A., Gonin, S., Prado de Carvalho, L., Specht, A., Grutter, T. "Agonist trapped in ATP-binding sites of the P2X2 receptor," Proc Natl Acad Sci U S A, (2011) 108 (22), 9066-9071. ( DOI: 10.1073/pnas.1102170108 ).
  • Jiang, R., Miyamoto, A., Martz, A., Specht, A., Ishibashi, H., Kueny-Stotz, M., Chassaing, S., Brouillard, R., de Carvalho, L. P., Goeldner, M., Nabekura, J., Nielsen, M., Grutter, T. "Retrochalcone derivatives are positive allosteric modulators at synaptic and extrasynaptic GABA(A) receptors in vitro," Br J Pharmacol, (2011) 162(6), 1326-1339. (DOI: 10.1111/j.1476-5381.2010.01142.x).