139 publications disponibles
Articles scientifiques
- Microglial P2X4 receptors are essential for spinal neurons hyperexcitability and tactile allodynia in male and female neuropathic mice, iScience | 2023
Co-auteur(s) : Damien Gilabert - Alexia Duveau - Sara Carracedo - Nathalie Linck - Adeline Langla - Rieko Muramatsu - Friedrich Koch-Nolte - François Rassendren - Thomas Grutter - Pascal Fossat - Eric Boué-Grabot - Lauriane Ulmann - Optical control of PIEZO1 channels, Nature Communications | 2023
Co-auteur(s) : Francisco Andrés Peralta - Melaine Balcon - Adeline Martz - Deniza Biljali - Federico Cevoli - Benoit Arnould - Antoine Taly - Thierry Chataigneau - Thomas Grutter - Untangling Macropore Formation and Current Facilitation in P2X7, International Journal of Molecular Sciences | 2023
Co-auteur(s) : Federico Cevoli - Benoit Arnould - Francisco Andrés Peralta - Thomas Grutter - Comparing transmembrane protein structures with ATOLL, Bioinformatics | 2021
Co-auteur(s) : Célien Jacquemard - Guillaume Bret - Thomas Grutter - Esther Kellenberger - P2X7 Receptors and TMEM16 Channels Are Functionally Coupled with Implications for Macropore Formation and Current Facilitation, International Journal of Molecular Sciences | 2021
Co-auteur(s) : Kate Dunning - Adeline Martz - Francisco Andés Peralta - Federico Cevoli - Eric Boué-Grabot - Vincent Compan - Fanny Gautherat - Patrick Wolf - Thierry Chataigneau - Thomas Grutter - Photo-isomerizable tweezers to probe ionotropic receptor mechanisms, Current Opinion in Pharmacology | 2021
Co-auteur(s) : Laurie Peverini - Kate Dunning - Francisco Andres Peralta - Thomas Grutter - Update of P2X receptor properties and their pharmacology: IUPHAR Review 30, British Journal of Pharmacology | 2021
Co-auteur(s) : Peter Illes - Christa E. Müller - Kenneth A. Jacobson - Thomas Grutter - Annette Nicke - Samuel J. Fountain - Charles Kennedy - Günther Schmalzing - Michael F. Jarvis - Stanko S. Stojilkovic - Brian F. King - Francesco Di Virgilio - Dual Gene Delivery Reagents From Antiproliferative Alkylphospholipids for Combined Antitumor Therapy, Frontiers in Chemistry | 2020
Co-auteur(s) : Boris Gaillard - Jean-serge Remy - Francoise Pons-lebeau - Luc Lebeau - P2X-GCaMPs as Versatile Tools for Imaging Extracellular ATP Signaling, eneuro | 2020
Co-auteur(s) : Matthias Ollivier - Juline Beudez - Nathalie Linck - Thomas Grutter - Vincent Compan - Francois Rassendren - Synthesis and Evaluation of Antitumor Alkylphospholipid Prodrugs, Pharmaceutical Research | 2020
Co-auteur(s) : Boris Gaillard - Jean-serge Remy - Francoise Pons-lebeau - Luc Lebeau - Design and evaluation of ionizable peptide amphiphiles for siRNA delivery, International Journal of Pharmaceutics | 2019
Co-auteur(s) : Patrick Neuberg - Alain Wagner - Jean-Serge Remy - Antoine Kichler - Erufosine (ErPC3) Cationic Prodrugs as Dual Gene Delivery Reagents for Combined Antitumor Therapy, Chemistry – A European Journal | 2019
Co-auteur(s) : Boris Gaillard - Cendrine Seguin - Jean-serge Remy - Francoise Pons - Luc Lebeau - Molecular determinants for agonist recognition and discrimination in P2X2 receptors, Journal of General Physiology | 2019
Co-auteur(s) : Federica Gasparri - Jesper Wengel - Thomas Grutter - Stephan A. Pless - An aqueous extract of the Anogeissus leiocarpus bark (AEAL) induces the endothelium-dependent relaxation of porcine coronary artery rings involving predominantly nitric oxide, Journal of basic & clinical physiology & pharmacology | 2018
Co-auteur(s) : Lazare Belemnaba - Sylvin Ouédraogo - Mathieu Nitiéma - Thierry Chataigneau - Innocent Pierre Guissou - Valerie Schini-Kerth - Bernard Bucher - Cyril Auger - Cationic Oligospermine-Oligonucleotide Conjugates Provide Carrier-free Splice Switching in Monolayer Cells and Spheroids, Molecular Therapy - Nucleic Acids | 2018
Co-auteur(s) : Marc Nothisen - Phanélie Perche-Létuvée - Jean-Paul Behr - Jean-Serge Remy - Mitsuharu Kotera - Co-delivery of anti-PLK-1 siRNA and camptothecin by nanometric polydiacetylenic micelles results in a synergistic cell killing, RSC Advances | 2018
Co-auteur(s) : Manon Ripoll - Marie Pierdant - Patrick Neuberg - Dominique Bagnard - Alain Wagner - Antoine Kichler - Jean-Serge Remy - New Insights Into Permeation of Large Cations Through ATP-Gated P2X Receptors, Frontiers in Molecular Neuroscience | 2018
Co-auteur(s) : Laurie Peverini - Juline Beudez - Kate Dunning - Thierry Chataigneau - Thomas Grutter - Polydiacetylenic nanofibers as new siRNA vehicles for in vitro and in vivo delivery, Nanoscale | 2018
Co-auteur(s) : Patrick Neuberg - Imene Hamaidi - Sabrina Danilin - Manon Ripoll - Veronique Lindner - Marc Nothisen - Alain Wagner - Antoine Kichler - Thierry Massfelder - Jean-Serge Remy - On the permeation of large organic cations through the pore of ATP-gated P2X receptors, Proceedings of the National Academy of Sciences | 2017
Co-auteur(s) : Mahboubi Harkat - Laurie Peverini - Adrien H. Cerdan - Kate Dunning - Juline Beudez - Adeline Martz - Nicolas Calimet - Alexandre Specht - Marco Cecchini - Thierry Chataigneau - Thomas Grutter - P2X2 Dominant Deafness Mutations Have No Negative Effect on Wild-Type Isoform: Implications for Functional Rescue and in Deafness Mechanism, Frontiers in Molecular Neuroscience | 2017
Co-auteur(s) : Yan Zhu - Juline Beudez - Ning Yu - Thomas Grutter - Hong-Bo Zhao - From solution to in-cell study of the chemical reactivity of acid sensitive functional groups, Organic and Biomolecular Chemistry | 2016
Co-auteur(s) : Sylvain Jacques - Geoffray Leriche - Michel Mosser - Marc Nothisen - Christian Muller - Jean-Serge Remy - Alain Wagner - From solution to in-cell study of the chemical reactivity of acid sensitive functional groups: a rational approach towards improved cleavable linkers for biospecific endosomal release, Organic and Biomolecular Chemistry | 2016
Co-auteur(s) : Sylvain A. Jacques - Geoffray Leriche - Michel Mosser - Marc Nothisen - Christian Muller - Jean-serge Remy - Alain Wagner - Molecular structure and function of P2X receptors, Neuropharmacology | 2016
Co-auteur(s) : Chloé Habermacher - Kate Dunning - Thierry Chataigneau - Thomas Grutter - Photo-switchable tweezers illuminate pore-opening motions of an ATP-gated P2X ion channel, eLife | 2016
Co-auteur(s) : Chloé Habermacher - Adeline Martz - Nicolas Calimet - Damien Lemoine - Laurie Peverini - Alexandre Specht - Marco Cecchini - Thomas Grutter - Preparation of poly(ethylene imine) derivatives with precisely controlled molecular weight, European Polymer Journal | 2016
Co-auteur(s) : Matthieu Landa - Mitsuharu Kotera - Jean-Serge Remy - Nezha Badi - Structure Tuning of Cationic Oligospermine–siRNA Conjugates for Carrier-Free Gene Silencing, Molecular Pharmaceutics | 2016
Co-auteur(s) : Marc Nothisen - Jérémy Bagilet - Jean-Paul Behr - Jean-Serge Remy - Mitsuharu Kotera - Synthesis of giant globular multivalent glycofullerenes as potent inhibitors in a model of Ebola virus infection, Nature Chemistry | 2016
Co-auteur(s) : Antonio Munoz - David Sigwalt - Beatriz Illescas - Joanna Luczkowiak - Laura Rodriguez-Perez - Iwona Nierengarten - Michel Holler - Jean-serge Remy - Kevin Buffet - Stéphane Vincent - Javier Rojo - Rafael Delgado - Jean-françois Nierengarten - Nazario Martin - pH-Responsive Nanometric Polydiacetylenic Micelles Allow for Efficient Intracellular siRNA Delivery, ACS Applied Materials and Interfaces | 2016
Co-auteur(s) : Manon Ripoll - Patrick Neuberg - Antoine Kichler - Nassera Tounsi - Alain Wagner - Jean-Serge Remy - Architectural and Functional Similarities between Trimeric ATP-Gated P2X Receptors and Acid-Sensing Ion Channels, Journal of Molecular Biology | 2015
Co-auteur(s) : Stephan Kellenberger - Thomas Grutter - Mannoside Glycolipid Conjugates Display Anti-inflammatory Activity by Inhibition of Toll-like Receptor-4 Mediated Cell Activation, ACS Chemical Biology | 2015
Co-auteur(s) : Vincent Flacher - Patrick Neuberg - Floriane Point - François Daubeuf - Quentin Muller - David Sigwalt - Jean-Daniel Fauny - Jean-Serge Remy - Nelly Frossard - Alain Wagner - Christopher G Mueller - Evelyne Schaeffer - Photopolymerized micelles of diacetylene amphiphile: physical characterization and cell delivery properties, Chemical Communications | 2015
Co-auteur(s) : Patrick Neuberg - Aurelia Perino - Emmanuelle Morin-Picardat - Nicolas Anton - Zeinab Darwich - Denis Weltin - Yves Mely - Andrey Klymchenko - Jean-Serge Remy - Alain Wagner - Spiro Diorthoester (SpiDo), a Human Plasma Stable Acid-Sensitive Cleavable Linker for Lysosomal Release, Bioconjugate Chemistry | 2015
Co-auteur(s) : Geoffray Leriche - Marc Nothisen - Nadege Baumlin - Christian Muller - Dominique Bagnard - Jean-Serge Remy - Sylvain Jacques - Alain Wagner - Bio-specific and bio-orthogonal chemistries to switch-off the quencher of a FRET-based fluorescent probe: application to living-cell biothiol imaging, Chemical Communications | 2014
Co-auteur(s) : Coraline Egloff - Sylvain Jacques - Marc Nothisen - D Weltin - C Calligaro - Michel Mosser - Jean-Serge Remy - Alain Wagner - Selective Irreversible Chemical Tagging of Cysteine with 3-Arylpropiolonitriles, Bioconjugate Chemistry | 2014
Co-auteur(s) : Oleksandr Koniev - Geoffray Leriche - Marc Nothisen - Jean-Serge Remy - Jean Marc Strub - Christine Schaeffer-Reiss - Alain Van Dorsselaer - Rachid Baati - Alain Wagner - 'ENDOTHELIUM-INDEPENDENT AND ENDOTHELIUM-DEPENDENT VASORELAXATION BY A DICHLOROMETHANE FRACTION FROM ANOGEISSUS LEIOCARPUS (DC) GUILL. ET PERR. (COMBRETACEAE): POSSIBLE INVOLVEMENT OF CYCLIC NUCLEOTIDE PHOSPHODIESTERASE INHIBITION, African Journal of Traditional Complementary and Alternative Medicines | 2013
Co-auteur(s) : Lazare Belemnaba - Sylvin Ouedraogo - Cyril Auger - Thierry Chataigneau - Aristide Traore - Innocent Guissou - Claire Lugnier - Valerie Schini-Kerth - Bernard Bucher - Cell-penetrating cationic siRNA and lipophilic derivatives efficient at nanomolar concentrations in the presence of serum and albumin, Journal of Controlled Release | 2013
Co-auteur(s) : Phanelie Perche - Marc Nothisen - Jeremy Bagilet - Jean-Paul Behr - Mitsuharu Kotera - Jean-Serge Remy - Do iodinated nano-emulsions designed for preclinical vascular imaging alter the vascular reactivity in rat aorta?, International Journal of Pharmaceutics | 2013
Co-auteur(s) : Nicolas Anton - Marina Atzenhoffer - Francois Daubeuf - Xiang Li - Valerie Schini-kerth - Barbara Delmotte - Thierry Vandamme - Thierry Chataigneau - Dynamic Micelles of Mannoside Glycolipids are more Efficient than Polymers for Inhibiting HIV-1 trans-Infection, Bioconjugate Chemistry | 2013
Co-auteur(s) : Evelyne Schaeffer - Laure Dehuyser - David Sigwalt - Vincent Flacher - Serena Bernacchi - Olivier Chaloin - Jean-Serge Remy - Christopher G Mueller - Rachid Baati - Alain Wagner - Dynamic Micelles of Mannoside Glycolipids are more Efficient than Polymers for Inhibiting HIV-1 trans-infection., Bioconjugate Chemistry | 2013
Co-auteur(s) : Evelyne Schaeffer - Laure Dehuyser - David Sigwalt - Vincent Flacher - Serena Bernacchi - Olivier Chaloin - Jean-Serge Remy - Christopher G Mueller - Rachid Baati - Alain Wagner - Exploring the ATP-binding site of P2X receptors, Frontiers in Cellular Neuroscience | 2013
Co-auteur(s) : Thierry Chataigneau - Damien Lemoine - Thomas Grutter - Moving through the gate in ATP-activated P2X receptors, Trends in Biochemical Sciences | 2013
Co-auteur(s) : Ruotian Jiang - Antoine Taly - Thomas Grutter - Optical control of an ion channel gate, Proceedings of the National Academy of Sciences of the United States of America | 2013
Co-auteur(s) : Damien Lemoine - Chloe Habermacher - Adeline Martz - Pierre-Francois Mery - Nathalie Bouquier - Fanny Diverchy - Antoine Taly - Francois Rassendren - Alexandre Specht - Thomas Grutter - Polycationic Pillar 5 arene Derivatives: Interaction with DNA and Biological Applications, Chemistry - A European Journal | 2013
Co-auteur(s) : Iwona Nierengarten - Marc Nothisen - David Sigwalt - Thomas Biellmann - Michel Holler - Jean-Serge Remy - Jean-Francois Nierengarten - Grape-derived polyphenols improve aging-related endothelial dysfunction in rat mesenteric artery: role of oxidative stress and the angiotensin system, PLoS ONE | 2012
Co-auteur(s) : Noureddine Idris Khodja - Thierry Chataigneau - Cyril Auger - Valerie Schini-Kerth - Intermediate closed channel state(s) precede(s) activation in the ATP-gated P2X2 receptor, Channels | 2012
Co-auteur(s) : Ruotian Jiang - Antoine Taly - Damien Lemoine - Adeline Martz - Alexandre Specht - Thomas Grutter - Involvement of the cysteine-rich head domain in activation and desensitization of the P2X1 receptor, Proceedings of the National Academy of Sciences of the United States of America | 2012
Co-auteur(s) : Eva Loerinczi - Yogesh Bhargava - Stephen Marino - Antoine Taly - Karina Kaczmarek-Hajek - Alonso Barrantes-Freer - Sebastien Dutertre - Thomas Grutter - Juergen Rettinger - Annette Nicke - Ligand-Gated Ion Channels: New Insights into Neurological Disorders and Ligand Recognition, Chemical Reviews | 2012
Co-auteur(s) : Damien Lemoine - Ruotian Jiang - Antoine Taly - Thierry Chataigneau - Alexandre Specht - Thomas Grutter - Molecular mechanisms of the cardiovascular protective effects of polyphenols, British Journal of Nutrition | 2012
Co-auteur(s) : Ramaroson Andriantsitohaina - Cyril Auger - Thierry Chataigneau - Nelly Etienne-selloum - Huige Li - M Martinez - Valerie Schini-kerth - Ismail Laher - Natural product extract of Dicksonia sellowiana induces endothelium-dependent relaxations by a redox-sensitive Src- and Akt-dependent activation of eNOS in porcine coronary arteries, Journal of Vascular Research | 2012
Co-auteur(s) : Yanna Rattmann - Eric Anselm - Jong-Hun Kim - Stéphanie Dal-Ros - Cyril Auger - Obdulio G Miguel - Adair R Santos - Thierry Chataigneau - Valérie Schini-kerth - Tightening of the ATP-binding sites induces the opening of P2X receptor channels, EMBO Journal | 2012
Co-auteur(s) : Ruotian Jiang - Antoine Taly - Damien Lemoine - Adeline Martz - Olivier Cunrath - Thomas Grutter - Agonist trapped in ATP-binding sites of the P2X2 receptor, Proceedings of the National Academy of Sciences of the United States of America | 2011
Co-auteur(s) : Ruotian Jiang - Damien Lemoine - Adeline Martz - Antoine Taly - Sophie Gonin - Lia de Carvalho - Alexandre Specht - Thomas Grutter - Cationic Polydiacetylene Micelles for Gene Delivery, Bioconjugate Chemistry | 2011
Co-auteur(s) : Emmanuelle Morin - Marc Nothisen - Alain Wagner - Jean-Serge Remy - From Toxins Targeting Ligand Gated Ion Channels to Therapeutic Molecules, Toxins | 2011
Co-auteur(s) : Adak Nasiripourdori - Valerie Taly - Thomas Grutter - Antoine Taly - Fruit juice-induced endothelium-dependent relaxations in isolated porcine coronary arteries: evaluation of different fruit juices and purees and optimization of a red fruit juice blend, Food & function | 2011
Co-auteur(s) : Cyril Auger - Jong-Hun Kim - Sandrine Trinh - Thierry Chataigneau - A Popken - Valérie Schini-kerth - Gene delivery with polycationic fullerene hexakis-adducts, Chemical Communications | 2011
Co-auteur(s) : David Sigwalt - Michel Holler - Julien Iehl - Jean-françois Nierengarten - Marc Nothisen - Emmanuelle Morin - Jean-Serge Remy - MMT, Npeoc-protected spermine, a valuable synthon for the solid phase synthesis of oligonucleotide oligospermine conjugates via guanidine linkers, Bioorganic and Medicinal Chemistry | 2011
Co-auteur(s) : Phanelie Perche - Mitsuharu Kotera - Jean-Serge Remy - Retrochalcone derivatives are positive allosteric modulators at synaptic and extrasynaptic GABA(A) receptors in vitro, British Journal of Pharmacology | 2011
Co-auteur(s) : Ruotian Jiang - Akiko Miyamoto - Adeline Martz - Alexandre Specht - Hitoshi Ishibashi - Marie Kueny-Stotz - Stefan Chassaing - Raymond Brouillard - Lia de Carvalho - Maurice Goeldner - Junichi Nabekura - Mogens Nielsen - Thomas Grutter - Vascular Protection by Natural Product-Derived Polyphenols: In Vitro and In Vivo Evidence, Planta Medica | 2011
Co-auteur(s) : Valerie Schini-Kerth - Nelly Etienne-Selloum - Thierry Chataigneau - Cyril Auger - A Putative Extracellular Salt Bridge at the Subunit Interface Contributes to the Ion Channel Function of the ATP-gated P2X2 Receptor, Journal of Biological Chemistry | 2010
Co-auteur(s) : Ruotian Jiang - Adeline Martz - Sophie Gonin - Antoine Taly - Lia Prado De Carvalho - Thomas Grutter - Adenovirus-derived vectors for prostate cancer gene therapy., Human Gene Therapy | 2010
Co-auteur(s) : J de Vrij - R Willemsen - L Lindholm - R Hoeben - G Consortium - C Bangma - C Barber - J Behr - S Briggs - R Carlisle - W Cheng - I Dautzenberg - C de Ridder - H Dzojic - P Erbacher - M Essand - K Fisher - A Frazier - L Georgopoulos - I Jennings - S Kochanek - D Koppers-Lalic - R Kraaij - F Kreppel - M Magnusson - N Maitland - P Neuberg - R Nugent - M Ogris - Jean-Serge Remy - M Scaife - E Schenk-Braat - E Schooten - L Seymour - M Slade - P Szyjanowicz - T Totterman - T Uil - K Ulbrich - L van der Weel - W van Weerden - E Wagner - G Zuber - Fine-Tuning the Morphology of Self-Assembled Nanostructures of Propargyl Ammonium-Based Amphiphiles, The Journal of Physical Chemistry B | 2010
Co-auteur(s) : Emmanuelle Morin - Jean-Michel Guenet - David D. Díaz - Jean-Serge Remy - Alain Wagner - Proton Sponge Trick for pH-Sensitive Disassembly of Polyethylenimine-Based siRNA Delivery Systems, Bioconjugate Chemistry | 2010
Co-auteur(s) : Gaelle Creusat - Anne-Sophie Rinaldi - Etienne Weiss - Rkia Elbaghdadi - Jean-Serge Remy - Rita Mulherkar - Guy Zuber - Tailoring drug release profile of low-molecular-weight hydrogels by supramolecular co-assembly and thiol-ene orthogonal coupling, Journal of Materials Chemistry | 2010
Co-auteur(s) : David Diaz - Emmanuelle Morin - Eva Schoen - Ghyslain Budin - Alain Wagner - Jean-Serge Remy - Cationic siRNAs Provide Carrier-Free Gene Silencing in Animal Cells, Journal of the American Chemical Society | 2009
Co-auteur(s) : Marc Nothisen - Mitsuharu Kotera - Emilie Voirin - Jean-Serge Remy - Jean-Paul Behr - Zip Nucleic Acids: new high affinity oligonucleotides as potent primers for PCR and reverse transcription, Nucleic Acids Research | 2009
Co-auteur(s) : Valérie Moreau - Emilie Voirin - Clément Paris - Mitsuharu Kotera - Marc Nothisen - Jean-Serge Remy - Jean-Paul Behr - Patrick Erbacher - Nathalie Lenne-Samuel - Comparative models of P2X2 receptor support inter-subunit ATP-binding sites, Biochemical and Biophysical Research Communications | 2008
Co-auteur(s) : Guillaume Guerlet - Antoine Taly - Lia Prado De Carvalho - Adeline Martz - Ruotian Jiang - Alexandre Specht - Nicolas Le Novère - Thomas Grutter - Oligonucleotide−Oligospermine Conjugates (Zip Nucleic Acids): A Convenient Means of Finely Tuning Hybridization Temperatures, Journal of the American Chemical Society | 2008
Co-auteur(s) : Régis Noir - Mitsuharu Kotera - Bénédicte Pons - Jean-Serge Remy - Jean-Paul Behr - A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family, Nature | 2007
Co-auteur(s) : Nicolas Bocquet - Lia Prado De Carvalho - Jean Cartaud - Jacques Neyton - Chantal Le Poupon - Antoine Taly - Thomas Grutter - Jean-Pierre Changeux - Pierre-Jean Corringer - Dynamic Structural Investigations on the Torpedo Nicotinic Acetylcholine Receptor by Time‐Resolved Photoaffinity Labeling, ChemBioChem | 2006
Co-auteur(s) : Alexandre Mourot - Thomas Grutter - Maurice Goeldner - Florence Kotzyba‐Hibert - Implications of the quaternary twist allosteric model for the physiology and pathology of nicotinic acetylcholine receptors, Proceedings of the National Academy of Sciences | 2006
Co-auteur(s) : Antoine Taly - Pierre-Jean Corringer - Thomas Grutter - Lia Prado De Carvalho - Martin Karplus - Jean-Pierre Changeux - A chimera encoding the fusion of an acetylcholine-binding protein to an ion channel is stabilized in a state close to the desensitized form of ligand-gated ion channels, Comptes Rendus. Biologies | 2005
Co-auteur(s) : Thomas Grutter - Lia Prado De Carvalho - Virginie Dufresne - Antoine Taly - Markus Fischer - Jean-Pierre Changeux - Molecular tuning of fast gating in pentameric ligand-gated ion channels, Proceedings of the National Academy of Sciences | 2005
Co-auteur(s) : Thomas Grutter - Lia Prado De Carvalho - Virginie Dufresne - Antoine Taly - Stuart J. Edelstein - Jean-Pierre Changeux - Normal Mode Analysis Suggests a Quaternary Twist Model for the Nicotinic Receptor Gating Mechanism, Biophysical Journal | 2005
Co-auteur(s) : Antoine Taly - Marc Delarue - Thomas Grutter - Michael Nilges - Nicolas Le Novère - Pierre-Jean Corringer - Jean-Pierre Changeux - A model for non-viral gene delivery: through syndecan adhesion molecules and powered by actin, The Journal of Gene Medicine | 2004
Co-auteur(s) : Idit Kopatz - Jean-Serge Remy - Jean-Paul Behr - Effective polyethylenimine-mediated gene transfer into human endothelial cells, The Journal of Gene Medicine | 2004
Co-auteur(s) : Violeta Zaric - Denis Weltin - Patrick Erbacher - Jean-Serge Remy - Jean-Paul Behr - Dominique Stephan - Genuine DNA/polyethylenimine (PEI) Complexes Improve Transfection Properties and Cell Survival, Journal of Drug Targeting | 2004
Co-auteur(s) : Patrick Erbacher - Thierry Bettinger - Emmanuel Brion - Jean-Luc Coll - Christian Plank - Jean-Paul Behr - Jean-Serge Remy - Rational understanding of nicotinic receptors drug binding, Current Topics in Medicinal Chemistry | 2004
Co-auteur(s) : Thomas Grutter - Nicolas Le Novere - Jean-Pierre Changeux - An H-bond between two residues from different loops of the acetylcholine binding site contributes to the activation mechanism of nicotinic receptors, The EMBO Journal | 2003
Co-auteur(s) : Thomas Grutter - Lia Prado De Carvalho - Nicolas Le Novère - Pierre-Jean Corringer - Stuart Edelstein - Jean-Pierre Changeux - Red wine polyphenolic compounds inhibit vascular endothelial growth factor expression in vascular smooth muscle cells by preventing the activation of the p38 mitogen-activated protein kinase pathway., Arteriosclerosis, Thrombosis, and Vascular Biology | 2003
Co-auteur(s) : Min Ho Oak - Marta Chataigneau - Therese Keravis - Thierry Chataigneau - Alain Beretz - Ramaroson Andriantsitohaina - Jean-Claude Stoclet - Soon Jae Chang - Valerie Schini-kerth - Syntheses and biological properties of cysteine-Reactive epibatidine derivatives, Bioorganic and Medicinal Chemistry Letters | 2003
Co-auteur(s) : Christian Che - Grégory Petit - Florence Kotzyba-Hibert - Sonia Bertrand - Daniel Bertrand - Thomas Grutter - Maurice Goeldner - The Magnetofection Method: Using Magnetic Force to Enhance Gene Delivery, Biological Chemistry | 2003
Co-auteur(s) : Christian Plank - Ulrike Schillinger - Franz Scherer - Christian Bergemann - Jean-Serge Remy - Florian Krötz - Marina Anton - Jim Lausier - Joseph Rosenecker - Development of plasmid and oligonucleotide nanometric particles, Gene Therapy | 2002
Co-auteur(s) : Emmanuel Dauty - Jean-Paul Behr - Jean-Serge Remy - Intracellular Delivery of Nanometric DNA Particles via the Folate Receptor, Bioconjugate Chemistry | 2002
Co-auteur(s) : Emmanuel Dauty - Jean-Serge Remy - Guy Zuber - Jean-Paul Behr - Intracellular delivery of nanometric DNA particles via the folate receptor, Bioconjugate Chemistry | 2002
Co-auteur(s) : Emmanuel Dauty - Jean-Serge Remy - Guy Zuber - Jean-Paul Behr - Models of the extracellular domain of the nicotinic receptors and of agonist- and Ca 2+ -binding sites, Proceedings of the National Academy of Sciences | 2002
Co-auteur(s) : Nicolas Le Novère - Thomas Grutter - Jean-Pierre Changeux - Structural Reorganization of the Acetylcholine Binding Site of the Torpedo Nicotinic Receptor as Revealed by Dynamic Photoaffinity Labeling, ChemBioChem | 2002
Co-auteur(s) : Thomas Grutter - Sonia Bertrand - Florence Kotzyba-Hibert - Daniel Bertrand - Maurice Goeldner - Cysteine mutants as chemical sensors for ligand–receptor interactions, Trends in Pharmacological Sciences | 2001
Co-auteur(s) : Bernard Foucaud - Philippe Perret - Thomas Grutter - Maurice Goeldner - Dimerizable Cationic Detergents with a Low cmc Condense Plasmid DNA into Nanometric Particles and Transfect Cells in Culture, Journal of the American Chemical Society | 2001
Co-auteur(s) : Emmanuel Dauty - Jean-Serge Remy - Thomas Blessing - Jean-Paul Behr - Inhibition of hepadnaviral replication by polyethylenimine-based intravenous delivery of antisense phosphodiester oligodeoxynucleotides to the liver, Gene Therapy | 2001
Co-auteur(s) : M Robaczewska - S Guerret - Jean-Serge Remy - I Chemin - W-B Offensperger - M Chevallier - Jean-Paul Behr - A J Podhajska - H E Blum - C Trepo - L Cova - Nicotinic receptors in wonderland, Trends in Biochemical Sciences | 2001
Co-auteur(s) : Thomas Grutter - Jean-Pierre Changeux - Polyethylenimine-mediated gene transfer into pancreatic tumor dissemination in the murine peritoneal cavity, Gene Therapy | 2001
Co-auteur(s) : K Aoki - S Furuhata - K Hatanaka - M Maeda - Jean-Serge Remy - Jean-Paul Behr - M Terada - T Yoshida - Dimerizable Detergents as Gene Transfer Vectors, Journal of Liposome Research | 2000
Co-auteur(s) : Thomas Blessing - Emmanuel Dauty - Jean-Serge Remy - Jean-Paul Behr - Photoaffinity Labeling of Torpedo Nicotinic Receptor with the Agonist [ 3 H]DCTA: Identification of Amino Acid Residues Which Contribute to the Binding of the Ester Moiety of Acetylcholine, Biochemistry | 2000
Co-auteur(s) : Thomas Grutter - Laurence Ehret-Sabatier - Florence Kotzyba-Hibert - Maurice Goeldner - Protective copolymers for nonviral gene vectors: synthesis, vector characterization and application in gene delivery, Gene Therapy | 2000
Co-auteur(s) : D Finsinger - Jean-Serge Remy - P Erbacher - C Koch - C Plank - Systemic linear polyethylenimine (L‐PEI)‐mediated gene delivery in the mouse, Journal of Gene Medicine | 2000
Co-auteur(s) : Shao-Min Zou - Patrick Erbacher - Jean-Serge Remy - Jean-Paul Behr - The p21 cip1/waf1 cyclin-dependent kinase inhibitor enhances the cytotoxic effect of cisplatin in human ovarian carcinoma cells, Cancer Letters | 2000
Co-auteur(s) : H. Lincet - L. Poulain - Jean-Serge Remy - E. Deslandes - C. Duigou - P. Gauduchon - C. Staedel - Controlled Template-Assisted Assembly of Plasmid DNA into Nanometric Particles with High DNA Concentration, Bioconjugate Chemistry | 1999
Co-auteur(s) : Ming Ouyang - Jean-Serge Remy - Francis C. Szoka - Gene transfer with synthetic virus-like particles via the integrin-mediated endocytosis pathway, Gene Therapy | 1999
Co-auteur(s) : Patrick Erbacher - Jean-Serge Remy - Jean-Paul Behr - Molecular investigations on the nicotinic acetylcholine receptor, Molecular Neurobiology | 1999
Co-auteur(s) : Florence Kotzyba-Hibert - Thomas Grutter - Maurice Goeldner - Nicotinic Acetylcholine Receptor Probed with a Photoactivatable Agonist: Improved Labeling Specificity by Addition of Ce IV /Glutathione. Extension to Laser Flash Photolabeling, Biochemistry | 1999
Co-auteur(s) : Thomas Grutter - Maurice Goeldner - Florence Kotzyba-Hibert - Polyethylenimine but Not Cationic Lipid Improves Antisense Activity of 3′-Capped Phosphodiester Oligonucleotides, Antisense and Nucleic Acid Drug Development | 1999
Co-auteur(s) : Sonia Dheur - Nathalie Dias - Arthur Van Aerschot - Piet Herdewijn - Thierry Bettinger - Jean-Serge Remy - Claude Hélène - E. Tula Saison-Behmoaras - Size Reduction of Galactosylated PEI/DNA Complexes Improves Lectin-Mediated Gene Transfer into Hepatocytes, Bioconjugate Chemistry | 1999
Co-auteur(s) : Thierry Bettinger - Jean-Serge Remy - Patrick Erbacher - Transfection and physical properties of various saccharide, poly(ethylene glycol), and antibody‐derivatized polyethylenimines (PEI), Journal of Gene Medicine | 1999
Co-auteur(s) : Patrick Erbacher - Thierry Bettinger - Pascale Belguise-Valladier - Shaomin Zou - Jean-Luc Coll - Jean-Paul Behr - Jean-Serge Remy - Chitosan-Based Vector/DNA Complexes for Gene Delivery: Biophysical Characteristics and Transfection Ability, Pharmaceutical Research | 1998
Co-auteur(s) : Patrick Erbacher - Shaomin Zou - Thierry Bettinger - Anne‐Marie Steffan - Jean-Serge Remy - Convenient Polymer-Supported Synthetic Route to Heterobifunctional Polyethylene Glycols, Bioconjugate Chemistry | 1998
Co-auteur(s) : Thierry Bettinger - Jean-Serge Remy - Patrick Erbacher - Jean-Paul Behr - Gene transfer with lipospermines and polyethylenimines, Advanced Drug Delivery Reviews | 1998
Co-auteur(s) : Jean-Serge Remy - Bassima Abdallah - Maria Antonietta Zanta - Otmane Boussif - Jean-Paul Behr - Barbara Demeneix - Monomolecular collapse of plasmid DNA into stable virus-like particles, Proceedings of the National Academy of Sciences | 1998
Co-auteur(s) : Thomas Blessing - Jean-Serge Remy - Jean-Paul Behr - Polyethylenimine but Not Cationic Lipids Promotes Transgene Delivery to the Nucleus in Mammalian Cells, Journal of Biological Chemistry | 1998
Co-auteur(s) : Hélène Pollard - Jean-Serge Remy - Gildas Loussouarn - Sophie Demolombe - Jean-Paul Behr - Denis Escande - Size, diffusibility and transfection performance of linear PEI/DNA complexes in the mouse central nervous system, Gene Therapy | 1998
Co-auteur(s) : Daniel Goula - Jean-Serge Remy - Patrick Erbacher - M Wasowicz - G Levi - B Abdallah - BA Demeneix - Template Oligomerization of DNA-Bound Cations Produces Calibrated Nanometric Particles, Journal of the American Chemical Society | 1998
Co-auteur(s) : Thomas Blessing - Jean-Serge Remy - Jean-Paul Behr - Delivery of Polynucleotides with Polyamine Lipids and Polymers, Nucleosides and Nucleotides | 1997
Co-auteur(s) : B. A. Demeneix - Otmane Boussif - Maria Antonietta Zanta - Jean-Serge Remy - Jean-Paul Behr - Lipospermine-mediated gene transfer technique into murine cultured cortical cells, Journal of Neuroscience Methods | 1997
Co-auteur(s) : Brigitte Sola - Cathy Staedel - Jean-Serge Remy - Amina Bahr - Jean-paul Behr - Nicotinic Acetylcholine Receptor Labeled with a Tritiated, Photoactivatable Agonist: A New Tool for Investigating the Functional, Activated State, Bioconjugate Chemistry | 1997
Co-auteur(s) : Florence Kotzyba-Hibert - Pascal Kessler - Vincent Zerbib - Thomas Grutter - Christian Bogen - Kenneth Takeda - Akli Hammadi - Laurent Knerr - Maurice Goeldner - Gene Transfer with Multivalent Synthetic Vectors, Journal of Liposome Research | 1996
Co-auteur(s) : Jean-Serge Remy - Jean-Paul Behr - Efficient Gene Delivery with Neutral Complexes of Lipospermine and Thiol-Reactive Phospholipids, Biochemical and Biophysical Research Communications | 1995
Co-auteur(s) : Antoine Kichler - Jean-Serge Remy - Otmane Boussif - Benoît Frisch - Christophe Boeckler - Jean-Paul Behr - Francis Schuber - Synthesis and Evaluation as a Gene Transfer Agent of a 1,2-Dimyristoyl-glycero-3-pentalysine Salt, Chemistry Letters | 1995
Co-auteur(s) : Jean-Marc Weibel - Antoine Kichler - Jean-Serge Remy - Christian Gaiddon - Jean-Philippe Loeffler - Guy Duportail - Denis Heissler - Targeted gene transfer into hepatoma cells with lipopolyamine-condensed DNA particles presenting galactose ligands: a stage toward artificial viruses., Proceedings of the National Academy of Sciences | 1995
Co-auteur(s) : Jean-Serge Remy - Antoine Kichler - V. Mordvinov - Francis Schuber - Jean-Paul Behr - Gene Transfer with a Series of Lipophilic DNA-Binding Molecules, Bioconjugate Chemistry | 1994
Co-auteur(s) : Jean-Serge Remy - Claude Sirlin - Pierre Vierling - Jean-Paul Behr - High-Efficiency Transfection of Primary Human Keratinocytes with Positively Charged Lipopolyamine: DNA Complexes, Journal of Investigative Dermatology | 1994
Co-auteur(s) : Cathy Staedel - Zhongxue Hua - Thomas R Broker - Louise T Chow - Jean-Serge Remy - Jean-Paul Behr - Gene Transfer Optimization with Lipospermine-Coated DNA, DNA and Cell Biology | 1993
Co-auteur(s) : Fabrice Barthel - Jean-Serge Remy - Jean-philippe Loeffler - Jean-Paul Behr
Conférences
- New insights into P2X permeation | 2021
Co-auteur(s) : Thomas Grutter - Les cibles thérapeutiques de demain : de la structure moléculaire à la fonction | 2019
Co-auteur(s) : Thomas Grutter - Molecular engineering of ATP-gated P2X ion channels provides new insights into ion permeation and gating mechanisms | 2019
Co-auteur(s) : Thomas Grutter - Optical control of P2X receptors | 2019
Co-auteur(s) : Thomas Grutter - Permeation mechanisms of large cations in ATP-gated P2X ion channels | 2019
Co-auteur(s) : Thomas Grutter - Optical control of P2X receptors | 2018
Co-auteur(s) : Thomas Grutter - Opening of a P2X ion channel with light, Purinergic Signalling | 2014
Co-auteur(s) : Thomas Grutter - Optical dissection of gating in P2X receptors, Purinergic Signalling | 2014
Co-auteur(s) : Chloe Habermacher - Damien Lemoine - Adeline Martz - Alexandre Specht - Thomas Grutter - Optogating a powerful approach to control an ion-channel gate, Purinergic Signalling | 2014
Co-auteur(s) : Damien Lemoine - Chloe Habermacher - Adeline Martz - Pierre-Francois Mery - Nathalie Bouquier - Fanny Diverchy - Antoine Taly - Francois Rassendren - Alexandre Specht - Thomas Grutter - GRAPE-DERIVED POLYPHENOLS PERSISTENTLY IMPROVE THE AGING-RELATED ENDOTHELIAL DYSFUNCTION, PARTICULARLY THE EDHF COMPONENT, IN THE RAT MESENTERIC ARTERY: ROLE OF ROS, SKCa, IKCa AND THE ANGIOTENSIN SYSTEM, Journal of Vascular Research | 2012
Co-auteur(s) : Noureddine Khodja - Thierry Chataigneau - Cyril Auger - Valerie Schini-Kerth
Parties d'ouvrages
- Manipulation of ion channel gating with photoswitchable tweezers., Methods in enzymology | 2021
Co-auteur(s) : Kate Dunning - Thomas Grutter - Cationic Photopolymerized Polydiacetylenic (PDA) Micelles for siRNA Delivery, Nanotechnology for Nucleic Acid Delivery | 2019
Co-auteur(s) : Manon Ripoll - Patrick Neuberg - Jean-Serge Remy - Antoine Kichler - P2X Receptors, Neuronal Ion Channels | 2018
Co-auteur(s) : Annette Nicke - Thomas Grutter - Terrance Egan - Virus-like nanoparticles for Gene Therapy | 2006
Co-auteur(s) : Guy Zuber - D. Dalkara - Jean-Serge Remy - Molecular Vectors for Gene Delivery to Cancer Cells, Nucleic Acid Therapeutics in Cancer | 2004
Co-auteur(s) : Guy Zuber - Jean-Serge Remy - Patrick Erbacher - Pascale Belguise - Jean-Paul Behr - Taking lipospermines and polyethylenimine from in vitro to in vivo, Self-assembling complexes for gene delivery: From laboratory to clinical trial | 1998
Co-auteur(s) : Jean-Serge Remy - Daniel Goula - Anne-Marie Steffan - Maria Antonietta Zanta - Otmane Boussif - Jean-Paul Behr - Barbara Demeneix - Gene transfer with cationic amphiphiles, Liposomes in basic research and industry | 1995
Co-auteur(s) : Jean-Serge Remy - Claude Sirlin - Jean-Paul Behr
Productions de vulgarisation
- Des nanomachines photochimiques pour explorer le vivant | 2017
Co-auteur(s) : Thomas Grutter - Chloé Habermacher - Laurie Peverini - Les vecteurs non viraux de thérapie génique, médecine/sciences | 1996
Co-auteur(s) : Jean-Yves Legendre - Jean Haensler - Jean-Serge Remy